Cellulitis is a clinical diagnosis with several mimics and no gold standard diagnostic criteria. Misdiagnosis is common?! 🆕️⚡️⚡️Systematic Review & Meta-analysis The mean proportion misdiagnosed was 41% (95% CI 28 to 56% for random effects model. Ouch! link.springer.com/article/10.100…

With the latest CLSI breakpoints, tobramycin is the only reliable aminoglycoside for Pseudomonas if you ever need one (Susceptible: MIC ≤1) Amikacin: can still be used for UTI (Susceptible: MIC ≤ 16) Gentamicin: RIP ☠️

You can help free up nursing time by converting IV antibiotics to PO. Save 1 hr by changing an IV q8h antibiotic to PO! Consider a point prevalence analysis at your hospital to see how much time could be saved if 10% of courses were changed to PO! #ISAS23 @jpogue1 #IDTwitter

Conference abstracts accepted, but no publications?  It's a common story for residency research projects. As someone who'd experienced it 6 times... these are the reasons why many residency projects go NOWHERE.  Brace yourself, because it's time for some tough love.

UA shows UTI.

Long-acting cabotegravir-rilpivirine (CAB-RPV) is the biggest advance in HIV therapeutics in years. Here's a brief explainer why, and a killer classic movie clip. (Next up -- the limitations of this groundbreaking treatment, because there are plenty.) blogs.jwatch.org/hiv-id-observa…

We (or YOU, really!) have thoughts. Some highlights in diagnostic stewardship (removing UA/cx from order sets), ER interventions on following up on UA cx, and a "mindful pause" on diagnosis.... #ASPchat doi.org/10.1017/ash.20… doi.org/10.1017/ash.20… doi.org/10.1017/ash.20…

Contaminant x.com/shouldhaveapet…

For non ID colleagues and ID ICYMI these are the most important updates that you must know about the new CLSI "M100-Ed33"! Updated Aminoglycoside Breakpoints for Enterobacterales & Pseudomonas aeruginosa Background & Reasons for the Changes! 🌟Bookmark🌟 clsi.org/about/blog/ast…

Faster is better. 📄 Nice work! academic.oup.com/ajhp/advance-a… in AJHP

“The commonly used cutoff of 10 leukocytes/µL had a poor specificity (36%) and a sensitivity of 100%.” academic.oup.com/cid/article/76… in Clinical Infectious Diseases

Updated guidance from this week’s CDC COVID-19 Real-Time Learning Network (RTLN) Clinician Outreach call regarding vaccines for respiratory viral infections as we head into the fall! 💉😷🍂🍁

Things I do not care about when discussing UA's and urine cultures: ❌Pyuria/Leuk esterase + ❌Nitrites ❌Bacteria on microscopy ❌Growth of bacteria on cultures Things I do care about: ✅SYMPTOMS Everything else is just asymptomatic bacteriuria! #IDTwitter #MedTwitter

🏀 If you’ve ever wanted to throw a keyboard in a trash can to prevent an unnecessary urine culture from being ordered, this one is for you! 🗑️ Ps Connor you are an absolute star 🤩 #USAAW23 #WAAW2023 #BeAntibioticsAware

We are delighted to announce the publication of UTI WikiGuideline in JAMA Network Open. Thank you to the 54 experts from 12 countries for drafting. Special thanks to Snacks, PharmD, MPH and Alfredo J Mena Lora MD FIDSA for leading the effort. jamanetwork.com/searchresults?…

We are proud to present the next WikiGuidelines on UTI; providing the first comprehensive review of literature in the immense area of UTI in over FOURTEEN YEARS. Thanks to everyone who contributed. We truly hope this will make a difference in the care of patients!!!

"Based on available evidence from 30 RCTs....topical estrogen is effective at reducing recurrent UTIs in postmenopausal women." WHY IS NOT EVERY POSTMENOPAUSAL WOMEN ON THE PLANET OFFERED VAGINAL ESTROGEN FOR UTI PREVENTION??!! 30 Randomized controlled trials! THIRTY!

Proposed assessment framework for patients with suspected UTI who live in long-term care facilities from WikiGuidelines ⭐No more urinalysis or urine culture simply for altered mental state/smelly urine/cloudy urine ⭐If other causes of fever are present, skip the urine tests

“Unfortunately, I think the problem of antibiotic resistance is going to get worse before it gets better. I worry that my grandchildren won’t have access to effective #antibiotics.” Jason Newland on the urgent need for new antibiotics. #USAAW24 pew.org/4fkfOYQ