our final year Wellcome phd student ROTOR thesis!! Congratulations Brendan Farrell #thesistheend

New #preprint from our Integrative Membrane Biology group.

Great cover image by Dario de Vecchis and Antreas Kalli group for their study on Band3 featured in Biophysical Journal Understanding Life in Molecular Detail Leeds Integrative Membrane Biology

New publication from Integrative Membrane Biology by Pliotas Group and Jon Lippiat

A cryo-EM grid preparation device for time-resolved structural studies doi.org/10.1107/S20522…

Excited to announce that the Goldman Lab will be coming to Public Engagement Events Near You in March 2020 #AstburyConversation20 #BeCurious20

We’ve got an exciting #postdoc opportunity working on #membraneprotein #structuralbiology in close collaboration with @LarsJeuken Pliotas Group and Dr Antreas Kalli! Check it out here and please encourage anyone that could be interested to apply: jobs.leeds.ac.uk/vacancy.aspx?r…

Very proud to share the first #CryoEM studies by our LICAMM The Astbury Centre #TRPC team: Cryo-EM structures of human TRPC5 reveal interaction of a xanthine-based TRPC1/4/5 inhibitor with a conserved lipid binding site. biorxiv.org/content/10.110…

It's published! #ionchannels #kcnt1 #epilepsy Beth Cole (She/Her) Rachel Johnson Jeff H Dejakaisaya Fishwick Research Stephen Muench

It started out as a 10 week rotation project looking at particle behaviour in the ice, over 1 year later we finished it! Thanks to lots of people David Klebl Rebecca Thompson Michele Darrow Molly Gravett Dimitrios Kontziampasis @DCFMonteiro and more.. biorxiv.org/content/10.110…

#OPENACCESS: "In-Lipid Structure of Pressure-Sensitive Domains Hints Mechanosensitive Channel Functional Diversity" by Charalampos Kapsalis et. al. cell.com/biophysj/fullt… Pliotas Group @belab.bsky.social Yue (Mary) Ma Leeds Integrative Membrane Biology Understanding Life in Molecular Detail @ScienceLeeds BSRC St Andrews

So excited to see IMPROvER finally published!!! First first authorship together with Steven Harborne and Jessica B 🍾 Give it a go and stabilise your most loved/hated membrane protein :) nature.com/articles/s4159…

Took a while to get around the preferred orientation of HSPD1 but good to see the hard work of David Klebl and the team Matthew Feasey Emma Hesketh Robin Bon Neil Ranson Frank Sobott finally out. cell.com/iscience/fullt…

Check out our new preprint: Mechanical and molecular activation lead to structurally analogous MscL states biorxiv.org/content/10.110… Great effort by Bolin & Benjamin Lane, Frank Sobott Anton Calabrese Kalli Group 🧫➡️💻➡️📊 at Understanding Life in Molecular Detail @ScienceLeeds Leeds Integrative Membrane Biology Mass Spec Leeds

In our latest article we found structural correlation between pocket modification and tension activation in the MscL channel using pulsed EPR, HDX and MD: cell.com/structure/full… Bolin Benjamin Lane Anton Calabrese Frank Sobott Kalli Group 🧫➡️💻➡️📊 International EPR Society RSC_ESR Understanding Life in Molecular Detail