🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Attention gene editors! We are searching for faculty in gene editing (broadly defined) at UC Irvine: recruit.ap.uci.edu/JPF09319

Do you know all the ways you can get support through Safe Helpline? Hint: It’s not just through the phone. Learn more about how Safe Helpline can support you at safehelpline.pulse.ly/sa8zuckzwd.

Thanks Andreas Boland and KamenzLab for writing this Spotlight of @xtpablo and Oegema/Desai Labs 's excellent work, which my lab was privileged to participate in.

Andreas Boland and I wrote a Spotlight for @JCellBio highlighting the wonderful work of our colleagues @xtpablo, Oegema/Desai Labs, Lee Bardwell and more. Check out their paper and of course our summary. Worm power!

In Genetics class this week we explored the history of our field & its roots in Eugenics. I used it to frame the question: Should scientists just “Stay in the lab” or is it our duty to speak out when others lie about our science & use it to further their own political views? 1/n

The strain on scientific publishing direct.mit.edu/qss/article/do…

Exciting new work on transient protein-protein interactions mediated by short linear motifs (aka docking) from Peter Pryciak and colleagues: biorxiv.org/content/10.110…

The journal eLife will no longer receive a journal impact factor, the analytics firm Clarivate announced today. science.org/content/articl…

Honored to have our image on the cover of this month’s issue Nature Chemical Biology featuring the MrTAC paper (linked below)! 🔬🧫

In this review, Grace Bower & I discuss recent evidence showing that, unlike canonical enhancers, long-range enhancers located hundreds of kb from their target genes rely on additional mechanisms to ensure robust gene activation during mammal development sciencedirect.com/science/articl…

Our preprint is out nature.com/articles/s4146… In a new set of experiments, we screened a panel of rare and common variants from patients with Autism and identified variants in enhancers of OTX2 & Mir9-2 that reproducibly alter their activity in vivo! Huge congrats to Ethan Hollingsworth

The first story of my PhD out now in final published form, including new untested variants (see below)!

What is #DEI it's an approach to look for the best brightest and most qualified. Without #DEI we ignore qualified applicants, judge without rubrics, and don't give everyone equal access to opportunity.

How to Dismantle the U.S. Research Enterprise in 15 Days medium.com/p/how-to-disma… #research #funding #NIH #government

Today marks the beginning of OpenRxiv, which replaces bioRxiv and medRxiv, the world's largest preprint platform for life and medical science openrxiv

Faculty Neuroscience Searches Remain Open at UC Irvine. Depression Cluster Hire: School of Medicine Position: recruit.ap.uci.edu/JPF09507 Charlie Dunlop School of Biological Sciences: recruit.ap.uci.edu/JPF09508 Henry Samueli School of Engineering: recruit.ap.uci.edu/JPF09510 & more coming!

This Sexual Assault Awareness and Prevention Month, let’s turn awareness into action. Here's how you can make a difference: ●Start the Conversation: Break the silence and create a trusting environment. ●Educate & Empower: Spread the word about resources like Safe Helpline.

Sexual Assault Awareness and Prevention Month may be coming to an end, but our commitment to supporting those affected by sexual assault is ongoing. Safe Helpline is available 24/7, 365 days a year, offering a dedicated Telephone and Online Helpline. We're always here for you!

Happy #PRIDE 🏳️‍🌈🏳️‍⚧️ Wishing everyone a #PrideMonth filled with celebrations of love and identity in all its forms. You matter and you belong at UC 🩷❤️🧡💛💚🩵💙💜🤎🖤🩶🤍

Happy to share our recent work, led by Ethan Hollingsworth in which we discovered that poised chromatin sensitizes enhancers to aberrant activation by non-coding mutations, contributing to disease. UCI Charlie Dunlop School of Biological Sciences UC Irvine biorxiv.org/content/10.110…