Water = Life 💦 Discover why water can transmit infections and explore means of control and prevention with our MOOC about Water Borne Infectious Diseases on FUN ! 🗓️ Registration is already open : fun-mooc.fr/en/courses/wat… 🌍 Enroll now #WaterRights #PublicHealth #MOOC #Course

Our new review on the cell cycle-coordinated maintenance of the Vibrio bipartite genome! great collective work from our Foundry! Thanks to Théophile Niault , Jakub, Lamberioux Morgan and last but not least the BOSSSS : Marie-Eve VAL. Now with a functional link (hoepfully) journals.asm.org/doi/10.1128/ec…

Find out how Vibrios manage two chromosomes ! thanks to Théophile Niault , Jakub Czarnecki , Lamberioux Morgan and Didier Mazel ! journals.asm.org/doi/10.1128/ec…

A new history of integrons Thanks to: Didier Mazel @epcrocha Parissi Vincent Théophile Niault Egill Richard Baptiste Darracq Eloi Littner Frederic Lemoine HUBPasteur Biomics Institut Pasteur @GenGen_IP G. Millot, J. Cury, C. Vit, B. Néron, D. Lapaillerie.... nature.com/articles/s4156…

What a start for the PGB lab in 2024 with yet another integron story! This time we uncover how toxin-antitoxin cassettes have shaped the evolution of chromosomal integrons, turning them into giant genetic libraries for fast "à la carte" adaptation! tiny.cc/xwh0wz

Cassette recombination dynamics within chromosomal integrons are regulated by toxin-antitoxin systems | Science Advances science.org/doi/10.1126/sc…

Plasmids are essential drivers of bacterial evolution, but most of them lack conj° genes, yet they spread... @epcrocha and Manuel Ares Arroyo developed a computational method for discovering new oriTs, identifying 21 new oriTs in nosocomial pathogens plasmids biorxiv.org/content/10.110…

nature.com/articles/d4158…

Finally! After a long journey our latest NRPS engineering story is out at science.org/doi/10.1126/sc… thanks to the hard work of several members from the @HelgeBode_lab

Sedentary chromosomal integrons (SCIs) are biobanks of anti-phage defence systems! In a huge collaboration with the Didier Mazel lab, we showed that these flexible genetic platforms encode known defences and further discovered 16 new systems. A thread (1/n) doi.org/10.1101/2024.0…

Our paper about integrons and their fascinating content is on biorXiv🤩Go check out Eloi's thread for a sneak peek of what these big fellas are capable of !

My first PhD paper is out in mBio !(tinyurl.com/h83mh8vy) Oral bacteria often form mixed species biofilms where aggregation drives interspecies interactions. But how do they bind to each other? Here, we investigated Veillonella parvula aggregation with other bacteria . [1/6]

So happy that I can finally share the results of my first postdoc paper with Michael Baym!! Turns out plasmids are an amazing system to study multi-scale evolution and we can track within-cell and between-cell dynamics! Here’s a photo of plasmids competing inside cells in a colony (1/n)

Excited to share my primary PhD work! Vibrio isolates can produce peptide deformylase inhibitors that induce prophages in their lysogenic competitors. Not only is it SOS-independent, but also serves as the first example linking translational stress with prophage induction 👀 1/