mtDNA heteroplasmy dynamics are so complex, even paradoxical. To understand why, we combined precise mtDNA editing w/a new method SCI-LITE. In dividing cells, selection (not drift) acts on cell (not intracellular) fitness to shape population heteroplasmy. rdcu.be/dFDCY

Extremely happy to share our recently published review article published in Trends in Microbiology. A very interesting review on SNAREs and pathogenesis of intra-vacuolar bacteria IISc Bangalore

shaastramag.iitm.ac.in/news-brief/cho…

Jyotsna Sharma's JBC paper on ORMDL3 was highlighted in ASBMB today. asbmb.org/asbmb-today/sc…

Times of India coverage of Jyotsna Sharma's recent JBC paper.

What an insightful lecture! Many thanks to Prof. Samrat Mukhopadhyay Samrat Mukhopadhyay for visiting CSIR-CDRI and delivering a wonderful talk on biological condensates. #Congratulations to the organizers! CSIR, India

AcSIR on a Stellar Rise! We're ecstatic to share that AcSIR has achieved 11th position in the NIRF Ranking 2024 (Research Institutions). This isn't just a rank; it's a testament to relentless pursuit of knowledge and innovation. From #22nd rank in 2021 to #11th rank in 2024,

Excited to share our paper just out in Nature today! Proud of my amazing Postdoc Dr. Akriti Prashar for this outstanding work! Self-repairing mitochondria use novel recycling system, study finds sickkids.ca/en/news/archiv…

Glad to share this little piece referring to last paper published in nature by Prashar et al. Selective degradation of mitochondrial inner membrane through direct transfer to lysosomes Nature News & Views Andreas Reichert ReichertLab nature.com/articles/d4158…

Saziya' paper in JCI-INSIGHT.

J&J folds cardiovascular and metabolic drug unit endpts.com/jj-folds-cardi…

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Extremely delighted to share our recent publication showing how peroxisomes help in inter-organellar cholesterol transport! Now in EMBO Reports! CSIR-CDRI AcSIR DBT/WT India Alliance Great partnership Veena Ammanathan Prof. Dipshikha Chakravortty's Lab embopress.org/doi/full/10.10…?

Exciting report from Lahiri Lab group at CSIR-CDRI ! #Salmonella infection triggers SCV-peroxisome interactions. First-ever identification of a bacterial protein with PTS1, mediating lysosomal cholesterol transport to SCVs. 🦠🧬 Read more: embopress.org/doi/full/10.10… #Microbiology

Check this out!

Check out this awesome work! Congratulations David Pla-Martín

We identify a new mechanism of synovial fibroblast invasion in the rheumatoid arthritis patients. Mitochondrial calcium uniporter might be a crucial target in RA! Thankful to all the collaborators. Please have a look! sciencedirect.com/science/articl…

We are looking for one Project Research Scientist-II and one RA-1 position. Please send your CV with cover letter . Only very serious inquiries match the requirements. Visit at autophagylab.com or CCMB website for more details. Please repost if possible.

🚨 #JustPublished New study from Dr. Amit Lahiri’s group CSIR-CDRI shows how MCU drives cell migration in rheumatoid arthritis by pushing mitochondria to cell edges. Blocking MCU slows damage—offering a new therapeutic angle! CSIR, India 👏 Read it here: pubmed.ncbi.nlm.nih.gov/40188890/