I am deeply honored and humbled to have been elected as a member of EMBO. This recognition would not have been possible without the incredible contributions of my past and current research group members. Thank you for your hard work and dedication! helsinki.fi/en/hilife-hels…

Our cryoET study of Alzheimer's pathology is out! 🧠 In situ amyloid to 8.7 Å, mysterious plaque constituents & the intriguing in-tissue organisations of Aβ and tau filaments! Joshua Jenkins Nayab Fatima Tom O'Sullivan @drrenefrank & team 🤩 #teamtomo nature.com/articles/s4158…

Crafted with ❤️ for the scientific community and totally open-source! Don't hesitate to get in contact.

DynaMight from Sjors Scheres @MRC_LMB models continuous structural heterogeneity in cryo-EM datasets, leading to an improved reconstruction of the consensus structure. The study also explores the issue of overfitting when modeling structural flexibility. nature.com/articles/s4159…

⏰ Just 2 weeks left to apply for our Wellcome Medical Research Council 'Cryo-ET Sample Preparation Workshop 2024' eBIC Beamline Diamond Light Source! Learn about #CryoET, FIB-SEM, lamella prep and processing with a special workshop on STA in RELION 5 with CCP-EM Apply by Aug 31! 🔬🦠

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Super excited to share our latest work on the native in-cell organization of the mitochondrial respiratory chain 🥳 Using cryo-electron tomography🔬, we show how the respiratory complexes (and other complexes) are organized inside native mitochondria!  biorxiv.org/content/10.110…

Cryo-EM is a bit of an imaging miracle. We collect 2D images with stupid amounts of noise. We don’t know what we’re looking at, or from which way. Yet some how we can churn it over and get to see (actually see) how life works on molecular scales in 3D. How?

But surprisingly, there’s a lot of information in these representations what we simply don’t use. We estimate resolution, sure, but leave composition, motion, and more to visual analysis and speculation. We could dig for more, and that's my job.

I currently have positions for one PhD (liu.se/en/work-at-liu…) and one Postdoc (liu.se/en/work-at-liu…) open, funded with extra bells and whistles. You will have effectively unlimited compute power and time to explore your own interests, travel and conduct impactful science.

Dear cryo-EM women scientists, We want to honor you and your contributions at BPS 2025. This year, the Cryo-EM subgroup will honor a mid/senior-career woman scientist as the inaugural June Almeida awardee. June Almeida is the virologist who first discovered the coronavirus in

After thousands of microscope hours and several years of painstaking optimisation, Callie Glynn and I are very excited to share our latest manuscript. We outline our approach to investigate the molecular organisation within hippocampus tissue using cryo-ET.

This is the most detailed model of a human cell to date, obtained using x-ray, NMR and cryoelectron microscopy datasets. ‘Cellular landscape cross-section through a eukaryotic cell.’ - by Evan Ingersoll and Gael McGill.

CZII’s particle picking machine learning challenge is up and running. There are already 1000 signups on Kaggle. Follow this page for an introduction and links to all sorts of material and resources, including two preprints: cryoetdataportal.czscience.com/competition

🚨New paper at #NeurIPS2024! We present Hydra, a mixture of neural fields 🐉🐉🐉 for ab initio cryo-EM reconstruction of complex mixtures. Hydra is our attempt at pushing the boundaries for even more extreme forms of heterogeneity in cryo-EM 🤯. This was joint work with an