Long COVID in context - great friday read by Roxanne Khamsi So much immune biology yet to understand... “By the time you’re caring for the person, the pathogen is long gone, it’s just that it’s initiated this cascade of immune-mediated damage,” nytimes.com/2021/04/06/opi…

Overall thread by Andrei Slabodkin is interesting - but this point in particluar:

Should we tell him that twitter is a thing?

Whole thread is good re proportion of cases driven by the B.1.1.7 variant, but the graph below really distills it.

Katrine Bosley To put this in further context though, almost 100% of UK cases have been B.1.1.7 since December, driving the wave which has now fallen dramatically.

I first worked w/ Michael Gilman >20 yrs ago(!) Biogen. Then, when he was at Stromedix, we each had Dan Lynch as our Board Chair. Then on the Board together Scholar Rock. Now, working together in a different context Arrakis Therapeutics. Each a great experience. Congrats, well-deserved.

"I've always wanted to be a part of something greater than myself." Long Island man Michael Kalberer explains why he joined a #CRISPR gene therapy trial for blindness. bit.ly/3f1Vija

Thoughtful thread, good advice.

I still have that shirt! I also liked using a riff on a Tip O'Neill quote: "all chemistry is local". Which admittedly played best in MA... Jen

Nice overview of mAbs' ascendance as a modality by Asher Mullard w/ great data. Early on, had to address foundational tech challenges (eg, humanization, yield, high concentration formulations); innovation continues today. Now 100 approved mAb products. nature.com/articles/d4157…

Fun long Friday read - fossils and plate tectonics of the Appalacian mountains.

Just listen to the way Giannis Antetokounmpo talks about ego and pride vs being humble and tell me that's not exactly the kind of lesson you'd want your kid to hear not just about sports but life as well. Like I said, even as a Bulls fan I root for him.

A Covalent Drug Discovery themed issue - that's cool. Jen @NMahanthappa

This is a good point. When anti-vaxxers cite their freedoms, constitutional rights, and–the whitest thing of all–the Founding Fathers to rail against vaccine mandates, do they know what they're talking about? What if I told you this happens EXACTLY every 100 years? A thread.

CRISPR technologies are powerful gene editing tools because they are programmable. We are excited to describe 3 new programmable systems, IscB, IsrB, and TnpB, some of the most abundant genes on the planet, with potential for gene editing. Science Magazine science.org/doi/10.1126/sc…

Fantastic hike, thank you Luke, Art, and Life Science Cares for the motivation. This little showed up on the hike down to give regards as well.

Press release | Galapagos appoints Paul Stoffels as Chief Executive Officer. Read the full press release here: glpg.com/press-release/…

Congratulations Lorenz Memorial Sloan Kettering Cancer Center for ISSCR Achievement Award. So well deserved. #stemcells #ISSCR2022

The just-announced U.S. Supreme Court decision in Dobbs v. Jackson Women’s Health Organization represents a stunning reversal of precedent that inserts government into the personal lives and health care of Americans. nej.md/3Aa5cKe

Extremely disappointed by today’s Supreme Court decision limiting a woman’s right to control her own health outcomes – especially when 2/3 Americans support that right. We must continue to fight to protect reproductive health. BioCentury #MyViews #RoeVsWade