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Important roadblocks in Microbiome research...until Tuesday at 10 am 😉: -genomic-like taxonomic depth and at the same time quantify hidden functions in a gut microbiome with high accuracy. -detect 1 bacteria among 1 million Interested ?👇 bruker.com/fr/news-and-ev…

📢Preprint alert Metaproteomics Initiative GutMicrobiota Health Host-Microbe Interactions Austrian Microbiome Mass Spec Pro Proteomics A quantum leap in microbiome research, metaproteomics, and proteomics biorxiv.org/cgi/content/sh… 🧵, below

SIMSEF 1.3 now available for acquisition of MALDI-TIMS-MS2s with the newest timsControl 5.1 release. Try it out now: github.com/SteffenHeu/sim…

Technical Note and Tutorial for the analysis of XL-MS data with PASEF, MeroX, ProXL, and Skyline! pubs.acs.org/doi/10.1021/ac… Only possible thanks to the support from Andrea Sinz Lab and the patience and willingness from Michael Riffle and the Skyline Project dev team!

Fragment ion intensity prediction improves the identification rate of non-tryptic peptides in timsTOF - Nature Communications nature.com/articles/s4146… --- #proteomics #prot-paper

Peptide chromatogram visualisation coming to our DIA proteomics software DIA-NN - this has been the top 1 most requested feature. Now we have implemented not one but two visualisation options :) Stay tuned

Friends, #FragPipe 22 has been released, and it's a big update! diaTracer enables spectrum-centric analysis of diaPASEF data. Skyline integration. Koina server for more deep-learning prediction options. DDA+ mode for ddaPASEF. DIA glycoproteomics and new chemoproteomics workflows

Searching your diaPASEF data for unknown modifications (Open) non-common PTMs or semitryptic peptides directly w/o need for spectral libraries? Here you go! biorxiv.org/content/10.110…

Introducing #diaTracer for diaPASEF data! Extending our DIA-Umpire concept to IM data it performs 3D (m/z, IM, RT) processing to generate DDA-like “pseudo-MS/MS” spectra, enabling 'library-free' analyses including PTM, nonspecific, and even open searches! biorxiv.org/content/10.110…

High-throughput proteome profiling with low variation in a multi-center study using dia-PASEF biorxiv.org/cgi/content/sh… #biorxiv_sysbio

A new resource to assist with scalable & multiplied single-cell proteomics. It describes a workflow using nPOP and plexDIA on timsTOF systems. scp.slavovlab.net/protocols#reso… bruker.com/en/products-an…

To get there was quite a journey, but finally it is out: Our massive High-Throughput #Proteomics study on sepsis with >4500 LCMS runs using #Evosep, #Bruker #TimsTOF and #Fragpipe: science.org/doi/10.1126/sc…

Excited to announce DIA-NN version 1.9, our software suite for proteomics data processing! A range of cool new features and general performance improvements. We consider it the most significant update in the history of DIA-NN. github.com/vdemichev/DiaN…

Thrilled to finally see µPhos published in Mol Syst Biol! A big thank you to Florian Meier, Sean Humphrey and all other coauthors for this exciting journey! Check out our greatly improved and extended story on how to unlock the true power of phosphoproteomics: embopress.org/doi/full/10.10…

The #mdcBerlin and Bruker are proud to announce the launch of the MDC – Bruker Center of Excellence for #SingleCellOmics! 🎉 Join us on July 8th at MDC-BIMSB to learn more about the center's mission and goals. Full program and registration 👉 mdc-berlin.de/MDC_Bruker_Cen…

Proteomics goes viral! We present vPro-MS to identify human-pathogenic viruses in patient samples from diaPASEF/DIA data. We developed a peptide library covering the human virome from 20,000 genomes, which enables highly specific detection (>99,9%) using vProID scoring.

tidyplots Time to say goodbye to ggplot2?🫡 "a significant reduction of code complexity" vs ggplot2 cran.r-project.org/web/packages/t… Jan Broder Engler bioRxiv 2024 biorxiv.org/content/10.110…