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Dorado is 1.0! 🎉 This London Calling release updates our DNA and RNA models to v5.2 with a new suite of mod models that are higher accuracy, lower FP rates, and significantly faster. - Introducing dorado variant 👀 - HAC error rate is down over 25%. - New 2’Ome mod models

With the increased capabilities of Hopper and Blackwell GPUs for machine learning inference and the optimisations in Dorado v1.0 we are introducing a new class of model “hyper” for Q28+ simplex accuracy available on request #nanoporeconf

ARTIC 2 is here! birmingham.ac.uk/news/2025/ambi…

PhD opportunity! findaphd.com/phds/project/t…

PhD opportunity! findaphd.com/phds/project/m…

Today any T2T Plant 🌱 Genome Assembly is a Push of the Button and Alexander Wittenberg and his team are providing excellent Assembly Services at KeyGene in Wageningen, the Netherlands 🇳🇱 Oxford Nanopore #nanoporeconf

Oxford Nanopore Tech Update LC2025. My full analysis of what this means for NGS and Multi-Omics, including the new Proteomics PoC. open.substack.com/pub/albertvile…

Hey Grok judging from X activity alone evaluate whether the top DNA sequencing companies are more party organizers or DNA sequencing tech providers 🤣

Have you requested a quote from PacBio online for a sequencer without getting one?

Announcing myloasm, a new long-read (ONT R10/PacBio) metagenome assembler. With Heng Li. myloasm-docs.github.io

Got a rare chance to do some field work and spotted a fox while looking for some sediment samples.

Biases from Oxford Nanopore library preparation kits and their effects on microbiome and genome analysis. #nanopore #genome doi.org/10.1186/s12864…

Dorado 1.0.0 gives the 5090 Oxford Nanopore basecalling datapoint a big boost🚀 (Likely the case for many of the other GPUs as well. If you have one of the GPUs on the list consider adding a v1 datapoint github.com/Kirk3gaard/202…)

Thanks to whoever quickly confirmed that it also goes for 4070 Ti Super getting 25 % faster 🎉

Can we please get Dorado 1.0.0+ in Oxford Nanopore minknow ASAP? 4090 also jumps quite a bit and is getting closer to support a full P2S with live sup 🎉

5090の速っ！？ もうデータ取りとベースコール派別物考えてしまうのもありだな…

Anyone know a faster tool for getting homopolymer info than counterr? I like the ability to report fraction of HPs at a given length called correctly for each of the 4 bases. github.com/dayzerodx/coun…

Rasmus Kirkegaard Not the same, but interesting nonethless homopolymer error rate estimates github.com/google/best