🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

📢 Attention postdocs! We are soliciting applications for the Méndez Scholars Program at Fred Hutch, which supports postdocs from excluded groups preparing for the academic job market. Apply here 👇👇👇 Due 2/1/2025 apply.interfolio.com/157983

Our paper with priya g Marc Germain Julien C and Cara Schiavon is now out in its final form!

Our work led by UC Berkeley MCB graduate student Trinity Cookis is now published in NatureStructMolBiol . Shout out to coauthors Alexandria Lydecker, Paul Sauer, and Vignesh Kasinath for their contributions and thank you to the suggestions from the reviewers that led to the final manuscript!

Excited to share our new preprint! Exceptional work by postdoc @MikeLange identifies the first #LipidDroplet lipid quality control pathway! Droplet-localized FSP1 safeguards stored neutral lipids, blocking their peroxidation & #ferroptosis induction.🤩biorxiv.org/content/10.110…

The Cryo-EM: the next 50 years Symposium held yesterday at UC Berkeley was a smashing success!!

Iyer, Akhmanova et al reveal that two centriolar proteins, CP110 & CPAP, show antagonistic activities at #microtubule + ends. Together, they impart very slow but processive microtubule polymerization & their interaction promotes robust #centriole formation hubs.la/Q033LnK30

Stunning paper Parkinson’s starts in kidney nature.com/articles/s4159…

‼️We are hiring! If you know anyone, please share/retweet. Thank you so much!‼️

Structure of the Thin Filament in Human iPSC-derived Cardiomyocytes and its Response to Heart Disease biorxiv.org/content/10.110…

Super excited to share our latest work just published! 🎉 Grateful for the support of my PI ⁦Takashi Akera⁩ and amazing collaborator@Melania Bruno ⁦Todd Macfarlan⁩ ! #Meiosis #ChromosomeBiology #CentromereEvolution nature.com/articles/s4146…

Vimentin filament transport and organization revealed by single-particle tracking and 3D FIB-SEM rupress.org/jcb/article-ab…

Another wonderful collaboration with Alan Brown lab. The Zhang lab together with Polina Lishko lab (co-first author Qingwei Niu) contribute the doublet microtubule structure from Crithidia fasciculata, a model organism that infects mosquitoes. science.org/doi/10.1126/sc…

Super interesting paper looking at the role of NFL. Clearly not only a biomarker of neurodegeneracion. cell.com/cell-reports/f…

Just find the recording of this symposium is on YouTube Cryo-EM: The Next 50 Years Symposium youtube.com/watch?v=Y6sB8a…

Mitochondrial complexity is regulated at ER-mitochondria contact sites via PDZD8-FKBP8 tethering nature.com/articles/s4146…

Despite the chaos and turmoil, our lab is blessed to have 3 new postdoctoral fellow openings and we would welcome scientists interested in: - combining single-molecule studies with cryo-EM - developing new protein design tools using bioinformatics and structure-based tools -

Pleased to share my latest review article with Taylor & Francis Research Insights, taking a deep dive into neuronal autophagy, how Huntingtin coordinates it, and how the process goes awry in Huntington’s disease. doi.org/10.1080/276941… #Neuroscience #Autophagy #HuntingtonsDisease

🔥 We caught SARS-CoV-2 in the act of membrane fusion—frame by frame! Using cryoET, we reveal the entire fusion sequence in near-native conditions—and how S2-targeting antibodies slam the brakes on it. Don’t miss it 👉 nature.com/articles/s4146… STRUBIOxford eBIC Beamline

Endoplasmic reticulum–mitochondria contacts are prime hotspots of phospholipid peroxidation driving ferroptosis nature.com/articles/s4155…

The MOSAIC reconfigurable microscope by Eric Betzig et al is finally out! MOSAIC integrates multiple advanced imaging techniques including light-sheet, label-free, super-resolution, and multi-photon, all equipped with adaptive optics: biorxiv.org/content/10.110…