I'm excited to share my lab's first preprint! It describes Affinity Map, a highly general method providing proteomic profiles of binding affinity for small molecules, peptides, and antibodies in cell lysate, organ extracts, and live cell surfaces. biorxiv.org/content/10.110…

Big day for the David lab! 🎉 Our Molecular Cell paper is out today- huge congrats to first authors Ifé Akano & Jake Hebert for leading this beautiful study uncovering SMARCA3 as a novel H3 E3 ligase that shapes heterochromatin regulation in colorectal cancer 🤩

Detecting Foldback Artifacts in Long Reads biorxiv.org/content/10.110… #biorxiv_bioinfo

Isidro Cortes-Ciriano Nature Methods Thanks! We missed your SAVANA paper during literature review as this artifact is not the main topic. We will cite in revision. CC Jakob Heinz

Outstanding work from the Geri lab! Global Protein-Ligand Binding Affinity Profiling via Photocatalytic Labeling biorxiv.org/content/10.110…

🤯Three (!!!) new papers today in Science Magazine on the application of generative AI for the de novo design of peptide/HLA binding molecules! Completely unique 3D structure and binding mode compared with natural TCRs and TCR mimics! Links to papers 👇

Another FASEB Hematologic Malignancies Meeting #HEMSRC with a terrific history introduction by Jonathan Licht, MD!

Ex-Alibaba CTO just made the boldest claim about AI & global power: “China is building the future of AI, not Silicon Valley.” He also revealed why AI by 2030 will look nothing like ChatGPT and how China’s approach is already decades ahead. Here are my top 7 takeaways: 🧵

Faculty Search for Assistant or Associate (Professor) Member - The Tow Center for Developmental Oncology & SKI Memorial Sloan Kettering Cancer Center nature.com/naturecareers/…

Fantastic presentation by Kevin Dolan as part of our Tri-I MD-PhD Gateways Summer Program ⁦Weill Cornell GSMS⁩ ⁦Weill Cornell Medicine⁩ ⁦Rockefeller University⁩ ⁦Memorial Sloan Kettering Cancer Center⁩