It’s wonderful that the first-in-human study of INX-315 is underway, led by my Peter Mac Cancer Centre colleague George Auyeung! Thanks to Cancer Discovery Tali Lev for your support of our work. And many thanks to Snow Medical Tom Snow for their unwavering support of our team! Peter Mac Research

#OnlineFirst: INX-315, a Selective #CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors, by Catherine Dietrich, Alec Trub, Patrick Roberts, Shom Goel et al. bit.ly/47NIuWr Incyclix Bio Peter Mac Cancer Centre

Research by Shom Goel and his lab, published in Cancer Discovery reports on a potent & selective CDK2 inhibitor developed by Incyclix Bio. The study shows that inhibiting CDK2 pharmacologically is a very promising strategy for 2 groups of high-risk cancers doi.org/10.1158/2159-8…

New research published in @CD_AACRo describes INX-315’s antitumor activity and ability to overcome drug resistance in #cancer. Learn more about our potent and selective #CDK2 inhibitor from our collaboration with Shom Goel and Peter Mac Research: petermac.org/about-us/news-…

Here is an open link to: Basic Science is not just a Foundation. (Nature Cell Biology, Volume 26, pages 8–10 (2024): rdcu.be/dv82R

Here's a piece I wrote with Suzannah Lyons Suzannah Lyons at 360info.global about therapy-induced #senescence in cancer. Hope you enjoy the read! Peter Mac Research Shom Goel 360info.org/are-zombie-can…

Peter Mac A/Prof Shom Goel has won a USD $3 million USDoD-Gov grant for his research into developing the next revolution in #breastcancer treatment. He's the first Australian to win the prestigious Era of Hope Scholar Award. Read more👇 petermac.org/about-us/news-…

Our team is very grateful to CDMRP for supporting our work on senescence in cancer. We are proud to receive this award and determined to use it wisely, bridging the gap between fundamental biology and development of new therapies. Peter Mac Cancer Centre UniMelb MDHS Snow Medical

New! Online now: Single-cell senescence identification reveals senescence heterogeneity, trajectory, and modulators dlvr.it/T5KfwF

Recruiting a new senior postdoctorate to join our group in University of Melbourne - Shom Goel oncodaily.com/71339.html #BreastCancer #Cancer #OncoDaily #Oncology #CancerEpigenetics

We are currently recruiting a senior postdoc to join our lab in Melbourne, Australia. Great projects and a bright and welcoming team - please consider applying (or contacting me directly) if you are interested. More here: nature.com/naturecareers/…

I am co-editing the research topic "Deciphering the Mechanisms of Therapy-Induced Senescence and Escape in Cancer" with Tareq Saleh and Halina Waś for Frontiers in Cell and Developmental Biology. Frontiers - Cell Biology Submissions are welcome! frontiersin.org/research-topic…

The value of ‘wasting time’ on deep thinking is often overlooked in a scientific ecosystem increasingly tainted by Wall Street’s productivity mindset. nature.com/articles/d4158…

I am sad to hear of the passing of Leonard Hayflick, a giant in aging research. One of the most amazing exchanges I’ve ever witnessed at a conference was related to the Hayflick limit. It was one of my first conferences as a PhD student, in beautiful Vancouver, Canada. Although

We are deeply saddened by Leonard Hayflick’s passing. His revolutionary discoveries opened new scientific avenues, and his inspirational story will endure. We would like to share the seminar he gave us, detailing the journey behind his groundbreaking work. youtu.be/QYjyceTOLhQ?si…

Happy to see our latest manuscript on the minimal set of markers to identify senescent cells in vivo out! Big effort with many excellent colleagues cell.com/cell/fulltext/… Demarialab ERIBA Research UMCG

Delighted to share our research Cancer Cell Memorial Sloan Kettering Cancer Center ! We explore the mechanisms behind variable #BreastCancer responses to CDK4/6 inhibitors. TP53 mutation is linked to lack of long-term disease control. cell.com/cancer-cell/fu…

Cartherics is excited to announce the publication of a paper in Molecular Therapy: Oncology, exploring innovative strategies to enhance CAR-T cell therapies for solid tumors like ovarian cancer. Read more: bit.ly/4l3Ohye #CancerResearch #Oncology

A/Prof Shom Goel finds playing chess with his son, both calming and exciting. Like a master chess player, @ShomGoel—a cancer biologist & oncologist at the @PeterMacC—anticipates cancer’s next move, thinking many steps ahead to outmaneuver it.

Congrats to A/Prof Shom Goel, has today been awarded the Gottschalk Medal from Australian Academy of Science! His research is reshaping how we treat and understand #breastcancer. A huge honour and well deserved. 👏 🔗 petermac.org/about-us/news-…