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My first publication with my Adimab colleagues: "Deamidation and isomerization liability analysis of 131 clinical-stage antibodies" tandfonline.com/doi/full/10.10…

here is a preprint about our protein design strategy for engineering biological response to new signals -- a fundamental process which cells can do beautifully, unless the signal is too weird. from Kortemme Lab & James Fraser (A$AP J): biorxiv.org/content/10.110…

our paper on designing protein biosensors is out! science.sciencemag.org/content/366/64…

Thank you Aaron Peskin and Shamann Walton for addressing governance over the past year+. We can and should walk and chew gum at the same time, and address governance as we pass a much needed revenue stream for #caltrain. We now have a good compromise to ensure that happens.

Very happy to finally release immuneML – an open-source python platform that streamlines development, application, and benchmarking of immune receptor machine learning for predicting immune status or antigen specificity (immuneml.uio.no). biorxiv.org/content/10.110… 1/10

Maybe they where gonna give super chump to wiper but thought it would be too weak compared to missiles So they gave it to this weapon instead. This also has Beakon.

Comp bio people: We want to compare/run your methods on these macromolecular modeling and design benchmarks: #PLOSONE dx.doi.org/10.1371/journa…

I'm at the #sfmayor debate with Tina Perica repping UCSFers - anyone have any questions you want me to ask?

First #sfmayor question manages to justify itself as a local question about global warming by jamming CleanPowerSF into the end.

My question re transportation sustainability fee (ht tim redmond) : Should developers pay for the full impacts of development? #sfmayor

Lee foes start coughing when Mayor Ed Lee goes over time - awesome LWV of San Francisco host says that everyone must have come down with a cold #sfmayor

Power of the incumbency - have to award Mayor Ed Lee the most-informed award for the night. #sfmayor

Verifying myself: I am kylebarlow on Keybase.io. 4ocO7ifC7O00Sl1cb4zyRUYVJ5Mb4lTT5eP5 / keybase.io/kylebarlow/sig…

a cool thing to remember is that whenever someone says "A.I." what they're really talking about is "a computer program someone wrote"

Felicity Jones is chosen to pass as an Imperial spy in Rogue One, I assume, based on her proper Imperial British accent.

I don't always know where #SFMuni will take me, but we always go into the future. #timetravel

Kyle's exit talk pscp.tv/w/bGYPUzM3MjU1…

Flex ddG: Rosetta ensemble-based estimation of changes in protein-protein binding affinity ... biorxiv.org/cgi/content/sh… #biorxiv_biophys

This is what my @sfmta_muni-obsessed 4-year-old does for fun. Need to know how to get from one point in #SanFrancisco to another? He's your guy.

congrats to Andrej Sali UC San Francisco on his election to the National Academy of Sciences! nasonline.org/news-and-multi… - one of heroes and most generous mentors!