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Clonal driver neoantigen loss under EGFR TKI and immune selection pressures nature Swanton Lab Quezada Lab Nicholas McGranahan James L Reading Maise Al Bakir nature.com/articles/s4158…

'water is transparent only within a very narrow band of the electromagnetic spectrum, so living organisms evolved sensitivity to that band, and that's what we now call "visible light". ' (found via HN)

The AIRR Diagnostics WG commentary is now available, wherein our members discuss both the challenges of current #AIRR-based #diagnostics, as well as the future directions that we see the field going into! #Immunology #tcr #bcr

New in Cancer Cell: Dr. Krijn Dijkstra and a team in the Quezada Lab, Voest Lab, and Swanton Lab established patient-derived #organoids to study immune invasion in #LungCancer. 🫁 Article: bit.ly/4ltQPp2 Discussion: bit.ly/3IzXLT9

Toothmarks on a fossilized bone tell a story of two mega-predators go.nature.com/4f4c3ri

Google has shared the system prompt that got Gemini 2.5 Pro IMO 2025 Gold Medal 🏅 paper now #1 trending on alphaXiv 📈

Anyone knows adam?

One of the most complex regions in the human genome revealed. To me, it was fascinating to combine genome assembly and pangenome graphs (PGR-TK in Fig. 3e) algorithm techniques to uncover the hidden diversity across human populations. #genomics #bioinformatics

For innate immune cells, the lack of diverse receptor rearrangements has prevented the study of clonal evolution of the innate immune system in human tissues and tumors. With @satpathology and @caleblareau, I’m delighted to share my PhD work that tackles this challenge:

My kind of graphical abstract

The Office of Management and Budget has superseded congress to limit NIH spending, directing institute and center directors to immediately halt the issuing of research grants, research and development contracts, and training awards during a “pause” of unspecified duration statnews.com/2025/07/29/tru… 💩👿

The coolest part of DOGE is that while they crippled medical research and cost-effective foreign aid programs, they also didn’t save any money.

🤯 🦠 🫁 ♋️ (nature) Respiratory viral infections awaken metastatic breast cancer cells in lungs nature.com/articles/s4158…

It is depressing, but all too predictable, how swiftly we’ve gone from the Social Science Genetic Association Consortium offering reassurances about the uses of behavioural polygenic scores to one of their lead authors marketing embryo selection for IQ

Overinterpreting underpowered multi-omics experiments - thecodon.substack.com/p/falling-in-t…

Man dies after taking animal dewormer Fenbendazole after reading online that it can treat cancer Quackery kills !!!! bbc.com/news/articles/…

Want to get 31% "younger" biologically? Play 90 mins of Bundesliga soccer. The catch? You're back to baseline within 24 hours. 🤣This isn't hype, it's a wild finding! A new study reveals GrimAge (the most robust epigenetic clock for mortality risk) shows a significant dip after a

As if everything wasnt already complicated enough

Network Motifs

🚨 PhD available in our lab 🚨 exploring blood immune multi-omics to detect lung cancer years before clinical diagnosis in a unique cohort of >10k CT screened individuals. ✅ Wet & dry lab ✅ September 2025 enrolment ✅ UK tuition fees only ucl.ac.uk/medical-scienc…