
Kalon Overholt
@kalon_overholt
Biological Engineering PhD Student @ MIT BE (he/him)
ID: 1272877293711634434
16-06-2020 13:05:12
62 Tweet
241 Takipçi
156 Takip Edilen


Learn more about Covid-19 vaccine development during this Wednesday's “COVID-19, SARS-CoV-2 and the Pandemic” lecture with Dan Barouch (Barouch Lab)! Join hosts Richard Young, @BatistaLab, and Kalon Overholt starting at 9am ET via livestream: bit.ly/700Covid






Excited to share our study mapping pathological human genetic variation to protein features likely involved in @BioCondensates dysregulation, out today in Developmental Cell! cell.com/developmental-… Congrats to Lena Afeyan, Susana Hawken, Richard Young and all co-authors! (1/)


Very excited to share our work out today in Developmental Cell mapping pathological mutations to protein features likely involved in condensate dysregulation across human disease. Salman Banani Lena Afeyan cell.com/developmental-…


Sequencing has revolutionized epidemiology. But how can we explore genomic hypotheses systematically? Opqua, a tool for simulating evolution in epidemiological models, is now peer-reviewed on Science Advances. 🧵👇 science.org/doi/10.1126/sc… #ScienceAdvancesResearch MIT Dept of BE

Check out our preprint showing that a large fraction of transcription factors bind #RNA, a feature important for gene control, development, and disease, out today in biorxiv! Congrats to Richard Young, Main Slot Online Gacor Hari Ini , and all co-authors! biorxiv.org/content/10.110… (1/)

Check out our paper on insulin receptor #condensates that are key for #insulinsignaling and become dysfunctional in insulin resistance #diabetes. Hope it will lead to treatments for patients! tinyurl.com/4f3ut4mn Richard Young @adallagnese Whitehead Institute MGHGIFellowship


1/n Our Region Capture Micro-C (RCMC) preprint by Viraat Goel Miles Huseyin is out today in Nature Genetics at rdcu.be/dbEuM See also MIT News story at news.mit.edu/2023/unprecede… with a nice 2-min video explainer youtube.com/watch?v=oybAJI… More details below:


Delighted that our study on transcription factors binding #RNA is now out in Molecular Cell! We provide evidence that TF-RNA binding is pervasive, important for gene control, development, and disease. Free paper access here for a limited time! authors.elsevier.com/c/1hM653vVUPNy… A 🧵:

“Our work suggests that if you want to develop a very efficacious drug, then you should know where the target of the drug is in the cell with respect to these compartments,” says Richard Young. ML helps predict where drugs accumulate in the cell: wi.mit.edu/news/machine-l…



Our first paper is out in Cell! Led by Rohith Rajasekaran, we present a programmable reaction-diffusion system that generates synthetic protein waves, oscillations, and patterns for spatiotemporal circuit design and FM data-encoding in human cells. authors.elsevier.com/a/1iN8ZL7PXmeeN

(1/n) Excited to share our new review by Jin(Harvey) Yang Nature Reviews Molecular Cell Biology We discuss: 1) spatiotemporal mechanisms of E-P interactions 2) mechanisms of enhancer selectivity 3) pros and cons of 3C and imaging based methods Brief summary thread below: nature.com/articles/s4158…

