Präzise Genreparatur mit hoher Effizienz: VBIO vbio.de/aktuelles/wiss…

Efficient single-copy HDR by 5' modified long dsDNA donors doi.org/10.7554/eLife.…

"A basic scientist is driven by curiosity and the desire to understand the mysteries of nature." This "is in contrast to applied and translational research, which is designed to solve specific problems, like treating a disease or creating a product."

A cluster of poster prizes! Congratulations to Paula Gutierrez Perez, Katharina Lust, and Clara Becker! #GfEIsSDB19

Die Universität Heidelberg hat sich mit ihrem Konzept der Comprehensive Research University – einer Volluniversität mit herausragender Forschungsstärke – im Wettbewerb um den Titel „Exzellenzuniversität“ durchgesetzt. uni-heidelberg.de/de/newsroom/un…

We are celebrating that ⁦Uni Heidelberg⁩ was successful in the #Exzellenzstrategie ! Thank everyone involved for pushing our university forward!

Angry white males stoked by Trump, Fox News, and social media write their lame manifestos, buy semi automatic weapons, and murder. When you speak of other human beings as “vermin” that “infest our country,” and allow easy access to guns, you get this.... bit.ly/2YpXVV0

Fantastic news! 👇

for the traceable loss-of-function approach in this paper, we used a "knock-out via targeted knock-in" strategy employing a splice acceptor-GFP linked to a very potent polyA/terminator sequence derived from the ocean pout's anti-freeze gene. #glow #CRISPR #knockout 🐟🥊 #medaka

Our last work is now published in Science Advances. Using #medaka_fish and computational modelling, we shows how signals from the #thymus and localisation of #thymocytes influence the lineage outcome, please click advances.sciencemag.org/content/7/29/e…

Wie werden unsere körpereigenen, krebs- und virenabwehrenden T-Zellen gebildet? ForscherInnen des Uniklinikums Tübingen, der Universität Heidelberg und des EMBL haben neue Erkenntnisse über diesen Prozess gewonnen: medizin.uni-tuebingen.de/de/das-kliniku…

Interested in #RareDiseases? join Thomas Thumberger & WittbrodtLab for #PhDposition We investigate Congenital Disorders of Glycosylation #CDG in translational #medaka fish models mutated based on the genetics of CDG-patients more details adb.zuv.uni-heidelberg.de/info/INFO_FDB$… please apply or RT!

If you happen to be at #GfE2022 in Uni Hohenheim visit Bettina (Bettina Welz) at her poster Number 7 to learn about why our hearts beat so differently. #medaka GfE #CRISPR

The fish lateral line is a nice example of life-long growth of a mechanosensory system. At #GfE2022, Karen Groß from Lazaro Centanin's lab (#COSHeidelberg) highlights mechanisms involved in sprouting new neuromast organs in #medaka. Background at doi.org/10.7554/eLife.…

Kaisa Pakari shows how to modulate PMM2 (activity) levels on the protein or genetic level. Using Base editing with a trick broadens the targeting range when baseeditors are used sequentially biorxiv.org/content/10.110… #medaka #baseediting #GfE2022 #glycosylation

At #GfE2022, Kaisa Pakari Kaisa Pakari from WittbrodtLab Thomas Thumberger presents recently developed genome editing wizardry, enabling her to engineer #medaka mutants of human diseases that would be out of reach for regular #CRISPR approaches. Check out biorxiv.org/content/10.110…

Congrats to all poster price winners! Also congrats to Dr. Tavhelidse-Suck the winner of the first if two GfE Dissertation Awards 2022.#GfE2022

And congrats to Dr. Bornhorst the winner of the second GfE Dissertation Award 2022. #GfE2022

thinkable.org/submission_ent…

Cell-autonomous factor (sox2) reprograms Medaka retina Müller glia to become regeneration competent WittbrodtLab biorxiv.org/content/early/…