Le 29 septembre c'est la Nuit Européenne des Chercheurs. Venez discuter Sciences dans des contextes spécieux et funs. A Marseille, au coin des minots, je parlerais du système immunitaire avec les enfants à partir de 4ans et leurs familles. Nuit Européenne des Chercheurs nuitdeschercheurs-france.eu/?2023#programme

The next European Thymus meeting ‘ThymE’ will be held from May 27 to 31, 2024 in Porto. Very glad to be part of the scientific organizing committee with my friend Nuno Alves. Join us for this exciting meeting ! #Tcells #Thymus #ThymE #Immunology

Medullary Thymic Epithelial Cell Antigen-presentation Assays: bio-protocol.org/en/bpdetail?id… (1/5)

Researchers Alexia Borelli, Cloé ZAMIT, and Magali Irla at Magali IRLA Lab, CIML have developed a rapid co-culture assay enabling the evaluation of antigen-presentation ability of mTEC to CD4+ T cells in an antigen-specific context. (2/5)

I am thrilled to present our new study out in nature where we measure aging at organ-level resolution in living people with large-scale plasma proteomics + ML! From Tony Wyss-Coray lab, co-led with former grad student Jarod Rutledge 1/12

Un poste d’Ingénieur d’étude CNRS est ouvert à mobilité en FSEP dans mon équipe au Centre d’Immunologie Marseille Luminy (CIML) dans le superbe cadre des calanques. Pour postuler, rendez-vous sur : mobiliteinterne.cnrs.fr/ords/afip/owa/…

New Research: The type 1 diabetes susceptibility locus Idd5 favours robust neonatal development of highly autoreactive regulatory T cells in the NOD mouse: Regulatory T lymphocytes expressing the transcription factor Foxp3 (Tregs) play an… frontiersin.org/articles/10.33… #immunology

Check out our new article in Front. Immunol. in which we identify that the type 1 diabetes susceptibility locus 5 is involved in a paradoxically higher development of high-affinity/autoreactivity Treg in newborn NOD mice. Thanks to all the authors for their great job !

Neuroimmunologists fans, we're looking for a post-doc to join our team :) !!

Thrilled to announce that our latest research at CIML showing that lymphotoxin acts as an inhibitory checkpoint of thymic Treg development is out in Nature Communications Link: rdcu.be/dSGOW @Irlalab Borelli Alexia Rafa Argüello #Treg #Thymus #Tcells #Immunology

Strong evidence showing that getting a PhD is extremely bad for your mental health. A new paper uses Swedish medical records and matches them to the full population of PhD students for which the authors could get gender and birth year data from 2006 to 2017. After some exclusion

One of the alluring and theoretical strategies for extending healthspan and longevity is to rejuvenate the thymus gland, promote an intact immune system. Now there's a way to do that in aged mice. science.org/doi/10.1126/sc… Science Translational Medicine

RANK ligand administration reversed age-dependent thymic involution and rejuvenated T cell immunity in mice Science Translational Medicine science.org/doi/10.1126/sc…

I remember being blown away when Magali IRLA Lab showed me these data CIML 🤯 - Exogenous RANKL substantially reverts thymic involution and improves T cell function in aged mice Science Translational Medicine science.org/doi/10.1126/sc…

Thrilled to share our latest research in Science Translational Medicine ! We show that RANKL administration reverses age-dependent thymic involution and rejuvenates T cell immunity. CIML #aging #thymus #Tcells #Immunology #Involution #Rejuvenation science.org/doi/10.1126/sc…

Really excited to share my new Post-doc paper published in Science Translational Medicine thanks to all the authors for their hard work ! RANKL treatment restores thymic function and improves T cell–mediated immune responses in aged mice | Science Translational Medicine science.org/doi/10.1126/sc…

New work connects #immunosenescence and the decline of the #thymus during aging with a drop in the ligand #RANKL—and shows RANKL treatment restores T cell production and rejuvenates immune responses in aged mice. Magali IRLA Lab Jérémy C. Santamaria (PhD) 🇫🇷 CIML scim.ag/3ZAqihe

RANKL treatment restores thymic function and improves T cell–mediated immune responses in aged mice science.org/doi/10.1126/sc…

New work connects #immunosenescence and the decline of the #thymus during aging with a drop in the ligand #RANKL—and shows RANKL treatment restores T cell production and rejuvenates immune responses in aged mice. Magali IRLA Lab Jérémy C. Santamaria (PhD) 🇫🇷 CIML scim.ag/3ZAqihe

🚨 We’re hiring a Postdoc! Join the Bajenoff Lab (CIML) to explore how macrophages shape tissue homeostasis and repair using cutting-edge models and imaging. 📍 Marseille, France 💰 €3,081–4,291 gross/month tinyurl.com/yp5kjds6 Apply now: [email protected] #PostdocJobs