A large-scale, whole-genome analysis in Science of over 12,000 cancers reveals previously unreported mutational signatures, including tumor-specific rare signatures. The findings could potentially help enhance personalized cancer treatments and diagnoses. scim.ag/12f

Excited to share this work by Dewar Lab PhD student Tata Kavlashvili in NatureStructMolBiol! Incredibly grateful to our collaborators David Cortez lab. Can't wait to see where this new direction takes us! #gelsnotcells #gelsandcells

We are delighted to share our work, now available in nature: nature.com/articles/s4158… Our scoring system can be accessed here: kinase-library.phosphosite.org Coming soon --> the tyrosine kinome and an improved system with many new functionalities & features! #TheKinaseLibrary #KL

Pleased to introduce our latest preprint, out now: “Cohesin-mediated DNA loop extrusion resolves sister chromatids in G2 phase”. We present new quantitative assays probing the conformation of replicated chromosomes by imaging and high-throughput DNA sequencing. A tweetorial: 1/9

Do you work on DNA repair, telomeres or cell cycle? Are you interested in their roles in development, cancer or other human diseases? Come to Melbourne for our conference! October 23-25. Registrations are now live! #ACDTM23 australiancellcycle.org

UQ Frazer Institute’s Dr MJK_Jones & his team are studying #kinases controlling DNA replication. They hope to develop new therapeutics targeting #cancer cells. They're also helping pharma better understand new kinase-targeting cancer drugs. Alexis Bonfim-Melo, PhD UQ News UQ Medicine

Interesting paper in Molecular Cell reveals how the clamped FANCD2:FANCI complex is removed from chromatin by FBXL12-mediated degrations. FBXL12 is a target for cancer therapy in high-cyclin E therapies. cell.com/molecular-cell…

Jones Lab inspiring next generation of Australian scientists. 😊💪🏻 MJK_Jones UQ News #FrazerInstUQ UQ Medicine

It was a joy to work with and inspire the next batch of future scientist. Thank you to SPARQ-ed for letting my group participate in this exciting opportunity. I strongly recommend the experience to other research groups at TRI.

1/ We have a big 8 days down under for telomere biology, DNA repair, genome stability, and the cell cycle. First - Sharon A. Savage, M.D. is visiting CMRI Friday 20 Octoberto present on her research related to genotype-phenotype relationships in telomere biology disorders.

Today in @Science_Magazine we report the laboratory evolution of compact degrons that enable targeted protein degradation triggered by an otherwise-inert small molecule, a multidisciplinary study that integrates organic chemistry, molecular glues, protein evolution, genome

ERC-funded positions now open❗️❕❗️ Join the Giunta Lab to understand human DNA evolution through the study of satellite repeats 🧬🧫🔬 APPLY here: euraxess.ec.europa.eu/jobs/239604 Pls RT 🔄🗨️🙏

I am seeking an enthusiastic postdoc to join my lab in Sydney to work on Nuclear Dynamics, DNA repair and genome stability. We offer innovative science, a competitive salary, and a supportive team. If you are interested, please get in touch with me: [email protected]

Really enjoyed working with Dr Kate Giles, Phillippa Taberlay and The Cesare Lab on this review. Roles for the 3D genome in the cell cycle, DNA replication, and double strand break repair #3DGenome  doi.org/10.3389/fcell.…

These new cyclin A/B inhibitors obliterate cancer cells that have lost tumor suppressors (p53 or RB) by hyperactivating E2F transcription factors and promoting apoptosis (cellular suicide) pathways. doi.org/10.1038/s41586…

Please see our review article in NSMB, “Mechanisms and genomic implications of BIR”. Adel Atari and Haoyang Jiang focus on mammalian BIR, its relationships to human disease, and genome engineering. Thanks to reviewers for helpful comments. nature.com/articles/s4159…

Happy to share new work from my lab by co-authors Peng and Lee-when BRCA1 is absent, RAD51 is busy authors.elsevier.com/sd/article/S10…

Pleased to see our research highlighted by UQ News news.uq.edu.au/2025-10-ai-pow…