A method to automatically explore mechanistic hypotheses from data using logic models, with Bryan Glazer #NIHfunded #NSFFunded frontiersin.org/articles/10.33…

Open sharing of GWAS summary data, lead in large part by the PGC, has been groundbreaking. If commercial use in violation of the terms and patient consent becomes acceptable it will be a disaster for genetics research and for recruiting future studies.

Our featured article 1: Principles and methods for transferring polygenic risk scores across global populations go.nature.com/3PbbGQ8 #Review by PRIMED Consortium methods working group

As a molecular biologist, my worst fear come true last night. 6 yo asked “how our body parts are made. Like, how do the arms and fingers know where to go?” She’s interested in developmental biology. Parents, talk to your kids about Wnt signaling before it’s too late.

Excited to share our new clonal hematopoiesis preprint!

CRISPR has gone too far

Master class in effective paper titles.

Friends don't let friends make bad charts! Chenxin Li, pulled together a lot of great advice for data visualization, with clear "do this, not that" examples for each item. Here are a few of my favorites, see the link below for more.

New manuscript about BCFtools/liftover, a tool that converts genetic variants between reference genome assemblies with better support for indels and multi-allelic variants: academic.oup.com/bioinformatics… 1/8

Consumers in the United States can now pre-order a genetically engineered plant for their home that glows continuously go.nature.com/3I1fjnm

just people living in the moment … not a single research proposal or grant application in sight

I've long suspected an important alternate role for chromothripsis in SCLC pathogenesis. Very excited to see these ground breaking results from Natasha Rekhtman MD PhD and Charlie Rudin

Why numbers are sometimes better than words. What people think you say when you say “little chance,” “probably not,” or “highly likely.”

Agreed! That's why I wrote ggpubfigs, a ggplot2 extension that *only colorblind-friendly color palettes. Easily make your figures colorblind-friendly with ggpubfigs! x.com/NKWhiteman/sta…

Visualizing RNA in live cells using CRISPR Doudna Lab Nature Biotechnology nature.com/articles/s4158…

Exclusive: These universities have the most retracted scientific articles A first-of-its-kind analysis reveals which institutions are retraction hotspots Read the full story here: go.nature.com/4gMhkmG

There’s sNOw place like Chapman Quad on a winter day. ❄️💙 #VandyMed #SnowDay

thrilling