Link here! guide.cryosparc.com/processing-dat…

Excited to share that our book chapter on #cryoEM epitope mapping, co‑written with my favourite collaborator Daniel Hurdiss, is now out! 🔬 It captures learnings from many biologics projects & we hope it’s a useful resource for structural immunologists! link.springer.com/protocol/10.10…

20k likes on this and it stays till the end of Summer League 🫨 We know you've got it in your bag Mamu

We like good beer. Drinking it. Making it. Selling it. Looking at it. Talking about it. Stein Bender, a super dank, piney, West Coast IPA, was brewed in collaboration with our friends at the legendary beer destination, The Bier Stein, for their 20th anniversary. Full of melony

When particles have orientation bias, the resulting maps are often streaked along the missing directions. In this case study, we cover why orientation bias produces anisotropic #cryoEM maps and how you may be able to recover from it! guide.cryosparc.com/processing-dat…

Very happy to share our preprint of a very long and extensive study of Na,K-ATPase complexes of neuron - and a key enzyme in the body. Active Conformations of Neuronal Na+,K+-ATPase isoforms and a Disease-Causing Mutant biorxiv.org/content/10.110…

Undruggable No More: AI Hits Disordered Proteins, Unlocks Therapy Targets David Baker’s Nobel Prize-winning lab has successfully designed high affinity binders to disordered proteins, expanding therapeutic access to over 50% of the human proteome genengnews.com/topics/artific…

The recently discovered giant virus PelV-1 has a tail of unprecedented length. Learn more: scim.ag/4ffxrtD News from Science

🤝 Winnipeg Jets

🚀 Boltz-2 NIM now does affinity prediction! 🔥 Co-fold protein-ligand complexes & rank hits in seconds. cuEquivariance + TensorRT → 2-3× speedup

On the Oregon Coast, we’re often at the mercy of the cold, unpredictable Pacific Ocean. Shifting currents, treacherous sands, high tides, distant tsunamis, weather patterns that defy explanation. You can’t rely on the Pacific Ocean. But you CAN rely on Vortex. This mighty West

First cryo-EM map of Apoferritin from our new 日本電子株式会社 / JEOL Ltd.【公式】 JEOL USA JEOL EUROPE cryoARM300-II with Direct Electron Apollo detector. Collected over night and processed in 1 day with CryoSPARC using all-default settings from only 76k particles. H/R B-factor=28 at 1.5A. Not too

Journals can’t find peer reviewers. Preprints aren’t taken seriously. Garbage papers slip through peer review. Meantime, AI is slowly taking over. Nature describes the current situation. I highly recommend reading the article. 📍 The summary (+ my comments): 1. We are facing a

Hernan Cortes

It’s time to play the gameeeee ⏰ Riverhawks playoff baseball tonight at RE/MAX Field 👀 🔗 tickets.gohawks.ca

Rober Saleh when a Aaron Glenn when a player makes a bone player makes a bone head mistake: head mistake:

My wife was looking at my timeline and asked what ‘puke 19’ is

Just having a little goof with our friends.