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Synonymous mutations have massive effects on protein activity. Never knew that. Take a protein & make a fast + slow-translated version. For one enzyme, fast translation caused 20% drop in activity. Simulation + experiments show "entangled states." Weird. nature.com/articles/s4155…

Scientists spend too much time taking “professional selfies”. A paper from PNAS describes what it takes to be a scientist today. Key points (that I always emphasize myself): #AcademicTwitter Academic Chatter™ #research

A fantastic achievement

😂 can relate

Please check out our latest publication providing further evidence that the time of the day of vaccine administration influences the adaptive immune response nature.com/articles/s4146…

This honestly blows my mind!

"His team is perfecting a system of tools to “say a protein,” that is, to describe its function out loud and have the computer provide its sequence. It also seeks to auto-complete a protein of which only part was provided, as if it were a Google search" english.elpais.com/science-tech/2…

The despair when you’ve been up for what feel like an entire day in the dark, and then your alarm goes off 😂 #kids

The blueprint is out!

The The Nobel Prize to Katalin Kariko and The Drew Weissman Lab wasn't just about how mRNA could be delivered, which led to Covid vaccines and *>20 million lives saved in 2021 alone*, but also a delivery platform for other vaccines vs pathogens, cancer, gene therapy and more

Join us for our next Infection and Immunity Seminar with Jordan Minnell Malaghan Institute. He will discuss mRNA vaccines against malaria tailored for liver-resident memory T cells. 🗓️7 Nov, 12:30 - 13:30 📍St. Mary's Campus/Online Find out more 👉 imperial.ac.uk/events/166150/…

A football match in 1599 between men of Bewcastle, England, and Armstrongs of Whithaugh, Scotland, was followed by ‘drynkyng hard’. Final score was two dead, 30 taken prisoner ‘and many sore hurt, especially John Whytfeild, whose bowells came out, but are sowed up againe’. 1/5

Excellent article by Elie Dolgin on the recent approval of the Arcturus saRNA vaccine! As Nathaniel Wang of Replicate Bioscience, Inc. put it, it's incredibly validating for the field 😀 Self-copying, self-amplifying, self-replicating, tomato, tomato... nature.com/articles/d4158…

Measles does more than just the acute infection It can wipe out large swaths of acquired immune memory by directly destroying the memory B cells, plasma cells, and T cells - causing people to become susceptible to infections they should be immune to: npr.org/sections/healt…

Is there anyone out there looking for an HFSP grant but doesn't have a friendly virologist to apply with? My last year as a new-PI so I would love to apply with other new-PIs. V interested in bio, chemists or AI new-PIs anywhere but Europe! Please write and we can talk ideas!

Fresh PhD Student 5th year Postdoc #AcademicChatter PhD Voice - Independently Run

mRNA vaccines produce rapid and precise immune responses against infectious diseases and cancers. Check out this Primer for details on the development of nanomaterials for mRNA vaccines and how they are designed: go.nature.com/3OEECyD