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Analyze_Blebs, our image analysis tool is now published: journals.plos.org/plosone/articl… The tool can be downloaded from GitHub: github.com/karlvosatka/an… Amazing work from our former Research Technician, Karl Vosatka!

Lab alumnus, Dr. Maria Ullo (Maria Ullo), represented the graduate school with a fantastic speech at commencement this year.

Today, we received an NOA for our MIRA (R35), thank you NIGMS (@NIGMS) for supporting our work. Looking forward to what we will learn about cancer and immune cell migration in confined environments over the next few years (Albany Med Health System).

Thank you News 10 for spreading the word (NEWS10 ABC). news10.com/news/science/a…

Congratulations to Alexa (non-Twitter) on her successful MS defense. Soon to be our new Research Associate/Lab Manager, we're lucky to have you! Albany Med Health System

A gene therapy was approved today by the FDA for Duchenne Muscular Dystrophy: fda.gov/news-events/pr…

Happy to share our newest pre-print, we demonstrate that Piezo1/Ca2+ activates INF2 to induce de-adhesion and amoeboid migration in confined environments: biorxiv.org/content/10.110…

During the tail end of her PhD in the lab, Maria Ullo (Maria Ullo) showed that THP-1 monocyte-like cells adopt an amoeboid mode of migration in confining channels, which requires cofilin-1: biorxiv.org/content/10.110…

We've added important new data to our recent pre-print (biorxiv.org/content/10.110…). While cells in confinement without INF2 firmly adhere to the micropattern, cells with INF2 will cross over the micropatterns using fast amoeboid (leader bleb-based) migration:

Solar eclipse today in upstate NY, totality was amazing!

My wife and I had the pleasure of attending the Gala of Hope (American Cancer Society) this last weekend, such an amazing event benefiting cancer research

Sharing our recent review on the role of Diaphanous related formins in regulating the amoeboid migration of cancer cells: onlinelibrary.wiley.com/doi/full/10.10…

Sharing out latest review with Alexa, "the biophysics of cell motility through mechanochemically challenging environments," out today in Current Opinion in Cell Biology: sciencedirect.com/science/articl…

Corning now offers sterile tips that come in a paper container, thus generating less plastic waste!

Happy to share our latest research article, "The activation of INF2 by Piezo1/Ca2+ is required for mesenchymal-to-amoeboid transition in confined environments," in Current Biology: authors.elsevier.com/a/1koXe3QW8SA2… Graphical abstract:

Have you seen the latest #openaccess review #article from Jeremy Logue's lab Logue Lab in #CYTOSKELETON? Have a look at it here: "Nucleating amoeboid cancer cell motility with Diaphanous related formins" onlinelibrary.wiley.com/doi/full/10.10…

Happy to share our new pre-print, "Targeting Cholesterol-Dependent Piezo1 Activation Impairs Amoeboid Migration in Melanoma Cells," led by our fabulous research technician, Sylvia Kuang. biorxiv.org/content/10.110…

I am happy to share that I am now a full collaborating member within the Cancer Host and Environment program at the University of Vermont Cancer Center: uvmcommunity.uvm.edu/portal/uvmcc_m…