Thanks for having us WMTV 15 News tinyurl.com/wur24bcn Big weekend for GI Oncology UW Health | Carbone Cancer Center find us @tenpinalleys Sunday all day!

Hey there! Our paper on ecDNA in pancreatic cancer is online nature.com/articles/s4158…. Thankful to our amazing friends and collaborators Peter Bailey, Andrea Sottoriva, and everyone supporting us through this journey Fondazione AIRC per la ricerca sul cancro, PRECODE Project, Fondazione Nadia Valsecchi ETS, Italian Pancreatic Cancer Community I-PCC,

What happens when compare organoids and clinical response--new paper out this week; peppered with our favorite topic of EGFR signaling resistance: bit.ly/44kjAPe Dustin Deming Melissa Skala Evie Carchman Mark Burkard supported by National Cancer Institute Doris Duke Foundation Conquer Cancer, the ASCO Foundation

Combination IO in #PDAC-- where are we? New review Justine Hung, MD Stanley Ozogbo MD, MPH summarizing checkpoint targets and dancing partners. UW Health | Carbone Cancer Center link.springer.com/article/10.100…

Thrilled to share our latest study just out in nature 😄A major milestone in our collaboration with ⁦Anirban Maitra⁩ Led by brilliant ⁦⁦⁦Guangsheng Pei⁩ ⁦⁦⁦⁦⁦⁦⁦⁦⁦⁦⁦Jimin Min⁩ ⁦⁦MD Anderson Cancer Center⁩ nature.com/articles/s4158…

Standing room only #advocates & #survivors PanCAN #purplestride in Waukesha this morning, quick stop on the drive down to AACR

Senior undergraduate Luke Koeppel taking award from AACR undergraduate poster competition! Will be graduate student #badger next fall UW Health | Carbone Cancer Center Center for Human Genomics and Precision Medicine #CUT&Tag

KRAS mutant and amplified selective inhibitor AMG410 in PDAC. PanCAN #developmentaltherapeutics #aacr25

Zoldonrasib KRAS G12D selective RAS inhibitor, excellent tolerance, 61% ORR with PRs seen at first scan in NSCLC. #AACR25 #expandaccess #PDAC

Dedicated grad student UW Health | Carbone Cancer Center Lauryn Flannagan shows 70x difference in IC50 of MRTX1133 as function of EGF stim. #organoids #KRAS mapped to pERK node.

Austin Stram UW Health | Carbone Cancer Center showing unique dependency of CDK7/9 against #FLC in engineered DNAJB1-PRKACA fusion model. Fibrolamellar Cancer #rarecancer Fight Liver Cancer

Luke Koeppel has fostered CDK9 + BET from the infancy of the lab's screens. #AACR25 we probe this by CUT&Tag for how it dismantles pTEF despite #MYC PanCAN UW Health | Carbone Cancer Center National Cancer Institute #developmentaltherapeutics

Always exciting to see the efforts of our amazing undergraduates: Sabrina Dean, Maria Martinez and Audrey Sawyer representing this past week across campus. #badgers UWResearch UW Health | Carbone Cancer Center

Doubling in the numbers of metabolically associated liver cancer deaths over 20 years. pubmed.ncbi.nlm.nih.gov/39694213/ Real problems we need to acknowledge Wisconsin Advocates for Public Health American Liver Foundation National

Great support for #rarecancer Appendix Cancer PMP Research Foundation today in Wisconsin for regional event connecting with patients and families about multiD care and precision medicine. #living4lindsey UW Health | Carbone Cancer Center

Givastomig 4-1BB bispecific with encouraging single agent antitumor ORR 16% across CLDN18.2 levels, including expression as low as 1+ in 11% of tumor cells bit.ly/4kAefbj Sam Klempner Sunnie Kim, MD Kristen Spencer #developmentaltherapeutics UW Health | Carbone Cancer Center

ICAM-1 knockout modeling on immune effectors: nature.com/articles/s4146… nice collaborative work from UW–Madison #stemcell #collaboration

Great weekend at AVAHO crafting the next frontier of VA research. Amazing time with home team Christopher Fletcher Jennie Piccolo, PharmD, BCOP to strategize bringing National Cancer Institute and practice changing #industrytrials to Veterans Affairs UW Health | Carbone Cancer Center

10 Years of Precision Tumor Board UW Health | Carbone Cancer Center University of Wisconsin Department of Medicine UW Dept of Pathology and Laboratory Medicine UW-Madison Department of Surgery UW–Madison What have we built and where do we go next? Come join us Overture Center for the Arts next week to find out: advancingprecisionmedicine.com/ape-apo-event-…