#100th Anniversary #Viewpoints :
Advancing chemokine research: the molecular function of CXCL8: buff.ly/4blYf8V

UW–Madison

Proteomic profiles of peritoneal fluid-derived small extracellular vesicles correlate with patient outcome in ovarian cancer: buff.ly/4aFAho5

Jesus Garcia-Donas HM HOSPITALES
#Oncology

The alanyl-tRNA synthetase AARS1 moonlights as a lactyltransferase to promote YAP signaling in gastric cancer: buff.ly/4bjE4Zd

#Metabolism

DNA topoisomerase II inhibition potentiates osimertinib’s therapeutic efficacy in EGFR-mutant non–small cell lung cancer models: buff.ly/3yjShXr

Winship Cancer Institute of Emory University
#Oncology #Therapeutics

Pharmacological suppression of the OTUD4/CD73 proteolytic axis revives antitumor immunity against immune-suppressive breast cancers: buff.ly/3ULrf2J

Winship Cancer Institute of Emory University
#Oncology #Therapeutics

RNF4 sustains Myc-driven tumorigenesis by facilitating DNA replication: buff.ly/3WMsS2K

Samuel R Bunting Rutgers University
#Genetics #Oncology

Intrinsic endothelial hyperresponsiveness to inflammatory mediators drives acute episodes in models of #Clarkson disease: buff.ly/4dGGPp4

Samir M. Parikh UTSW Nephrology
NIAID News

#VascularBiology

Excess glucocorticoids inhibit murine bone turnover via modulating the immunometabolism of the skeletal microenvironment: buff.ly/3K37i2n

#BoneBiology

#Review : Shear stress and pathophysiological PI3K involvement in vascular malformations: buff.ly/4al3KDy

part of #Review Series: buff.ly/49FhecX

Seyfried Lab Universität Potsdam

Noncanonical WNT5A controls the activation of latent TGF-β to drive fibroblast activation and tissue fibrosis: buff.ly/3V4WKGA

Heinrich-Heine-Universität Düsseldorf
#Dermatology #Pulmonology

#ClinicalMedicine :
LXR signaling pathways link cholesterol metabolism with risk for prediabetes and diabetes:

Duke University School of Medicine
#Metabolism

#Review by Nicolas Dupré, Antoine Drieu, and Anne Joutel Inserm: Pathophysiology of cerebral small vessel disease: a journey through recent discoveries: buff.ly/3wLCsZ0

#Cover : STING activation sensitizes malignant peripheral nerve sheath tumors to immunotherapy: buff.ly/3yk9d02

Image: MPNST (blue) targeted for immune destruction by infiltrating T cells (pink); Credit: Bandarigoda Somatilaka.
Lu Le UT Southwestern Medical Center

#Oncology

#Review :
Therapeutic vaccines for herpesviruses: buff.ly/3UTwy1t
NIAID News

#ResearchLetter :
Gravi-D peptide disrupts HDAC11 association with an AKAP to stimulate adipocyte thermogenic signaling: buff.ly/4ae03zr

CU School of Medicine
#CellBiology #Therapeutics

#ResearchLetter :
Adult and neonatal models of chemogenetic heart failure caused by oxidative stress: buff.ly/4btnNAp

Fotios Spyropoulos Brigham and Women’s Research
#Cardiology

#ClinicalMedicine :
Integrated longitudinal multiomics study identifies immune programs associated with acute #COVID_19 severity and mortality: buff.ly/3UUBKlO

Leying (Lexi) Guan Yale School of Medicine
#Immunology

BAP1 is required prenatally for differentiation and maintenance of postnatal murine enteric nervous system: buff.ly/4dvwSus

Children's Hospital
#Development #Gastroenterology

#Commentary :
STINGing away the pain: the role of interferon-stimulated genes: buff.ly/4bcpJ0z

Dr. Rajesh Khanna of the KhannaLabUF FLORIDA

Related article: buff.ly/4btpRZe

#Commentary :
A step closer to understanding how a diet high in simple carbohydrates may cause dysbiosis: buff.ly/3QCXz6O

John Y. Kao Shrinivas Bishu Michigan Medicine

Related article: buff.ly/3JPyIc0