We had previously shown that the composite pulm embolism shock score predicts normotensive shock in patients with intermediate risk PE. But does it predict adverse clinical outcomes? PERT Consortium Rachel Rosovsky Eric Secemsky MD MSc Dr Shariq Shamim Jay Giri Jay Mathews MD, MS, FACC, FSCAI

Landmark PERSEVERE trial announced European Society of Cardiology 2024 RCT for high risk massive PE: large bore thrombectomy vs standard of care. Mortality 20-30% with standard of care 1 past RCT in this group with only 8 patients. The “Golden Era of PE RCT” continues! sciencedirect.com/science/articl…

Prof Nicolas Meneveau announces the global #PERSEVERE RCT for acute high-risk PE in a full room at #ESCCongress. "PERSEVERE is the first RCT in high-risk PE in 40 years" #FlowTriever #PulmonaryEmbolism #RandomizedTrial #DataMatters #GoldenAge Jay Giri John Moriarty

RHEIA Trial: women w/ severe AS, TAVI using SAPIEN 3/SAPIEN 3 Ultra superior to surgery for primary composite end point of death, stroke, or rehospitalization at one year: superiority driven by lower rate of rehospitalizations. #ESC2024 #ESCCongress2024 European Society of Cardiology

Continuation versus Interruption of Oral Anticoagulation during TAVI: NEJM 🥸 Another TAVR trial: The POPular PAUSE TAVI trial - the names are great #ESCCongress2024 😱 Let's also keep it < 25 points:

🥸 🔟 Major vascular complications occurred more frequently in the continuation group (10.2% vs. 7.7%) 😱Concerns about the safety of uninterrupted anticoagulation during TAVI: bleeding 31.1. vs 21.3%

The OCEANIC-AF trial, comparing asundexian to apixaban in patients with atrial fibrillation was halted early due to a significantly higher incidence of stroke or systemic embolism in the asundexian group. The findings raise questions about the adequacy of factor XIa inhibition

For the critical care community these findings may be understood. For non-critical care providers - 24 hrs means limited time to reassess, escalate care, or transfer to another facility. The Golden Day slips by quickly. More to come. #Don’tSleepOnShock Sunil V. Rao Jason N. Katz

UFH or LWMH for patients with acute PE. Swing by our abstract at #ESCCongress2024. Haisum Maqsood Robert Zhang MD NYU Langone Health Glenn Fishman Tania Ahuja 👩🏻‍💻🫀 Houston Methodist PERT Consortium Rachel Rosovsky

In patients with de novo, non-complex coronary artery disease, irrespective of vessel diameter, a strategy of DCB angioplasty with rescue stenting did not achieve non-inferiority compared with the intended DES implantation in terms of the DoCE at 2 years. This is the first of a

1. On this Labor Day, a reminder that FTC has issued a rule banning noncompetes. Noncompetes trap millions of workers, blocking them from taking better jobs or starting their own business. Over 25,000 Americans commented on our proposal. Here are some of their stories:

Our publ in Lancet: IPD pooled analysis of all 6 RCTs in which 23,256 pts were treated with 1-yr DAPT vs. 2wks-3mos DAPT (median 78d) followed by ticagrelor monoRx. MACE favored short DAPT, and major bleeding and mortality were reduced. Similar results in CCS & ACS, even post-MI.

All, I would like to invite you to attend the upcoming 4th Annual Philadelphia Cardiovascular Congress on Thursday - Friday, October 24-25, 2024 at the Bellevue Hotel located in Philadelphia, PA. Register here: lnkd.in/eHYS2yw2 Michael Savage David L. Fischman Jefferson Health

Introducing the #PERSEVERE RCT, continuing our commitment to generating high-quality clinical evidence. ✔ 200 patients randomized 1:1 to #FlowTriever or standard of care ✔ High-risk PE patients ✔ Designed by internationally recognized leaders in PE Thank you to our clinical

Mark your calendar for the Jefferson Health Philly CV Congress Oct 24-25⤵️ With an all star faculty Konstadinos Plestis Nicholas Ruggiero Joe Bavaria, MD Gianluca Torregrossa Jay Giri Philippe Genereux Yevgeniy Brailovsky DO MSc FACC Daniel Frisch, MD Rebecca Marcantuono Consult Guys Omar Khalique Hugh Calkins Carin Gonsalves, MD, FSIR

This is a TOTAL mess Physicians face an average of 57 unique quality measures across 8 value-based contracts Many, if not most of these measures are worthless Administrative waste Burnout inducers Costly Takes away from real quality improvement

PE-TRACT enrolled its 200th participant today, courtesy of Dr. Kesselman and team at Stanford (my Alma mater). Onward! Andrew Kesselman MD RPVI Society of Interventional Radiology Sunil V. Rao Society for Vascular Medicine | SVM PERT Consortium North American Thrombosis Forum NIH NHLBI David J. Cohen, MD, MSc Professor Susan R Kahn #PETRACT

An epic rainbow over Philadelphia this evening.

Comprehensive #SCAIfellowsCourse on #PVI in beautiful Miami on Dec 11-15 2024 led by Dr Peter Monteleone Peter Monteleone, MD, FACC, FSCAI Learn the steps of #AdvancedEndovascular techniques scai.org/scai-2024-fell… Nikos Pyrpyris Suman Rao MD Shikha Jha M.D.🫀 Pooja Prasad, MD Vanessa Rodriguez Fuenmayor Orly Leiva, MD

Agreed! jamanetwork.com/journals/jamac…