Trait differences Q_{ST} and F_{ST} Details can deceive (Janis Liu, "Error rates in Q_{ST} vs. F_{ST} comparisons depend on genetic architecture") #sciku #evol2023 Janis Liu

So happy to have my first talk and make new friends at #evolution2023 !

I'm excited to share this new preperint with Matt Pennell and Doc Edge about the unifying mapping approaches within and between species biorxiv.org/content/10.110…

Second time at #TAGC24/PEQG! Presenting a poster tonight (785T) on my PhD work with Noah Rosenberg on mathematical properties of allele-sharing dissimilarities (and how they explain phenomena observed in human population-genetic data)! Part 1 paper at doi.org/10.1515%2Fsagm…

Eugenic movement and scientific racism: past, present, and future #TAGC24 panelists: Katrina Claw, Nathaniel Comfort, Steven Farber, Daniel HoSang, and Jazlyn Mooney, PhD

Two new preprints from my group today---this one was led by Dandan Peng with an assist from Obadiah Mulder. Dandan benchmarked a bunch of leading ARG-estimation methods with respect to a specific goal (1/n)

Second preprint from my group today---this one is led by Feriel Ouerghi . In this one, we discuss a previously proposed method for building forensic likelihood ratios from sequencing reads (1/n)

Excited to share this new preprint with @spence_jeffrey_ and Doc Edge in which we developed a method to infer demographic history and mutation rates from millions of genomes, and applied it to gnomAD v4 data. Read on for a brief thread! biorxiv.org/content/10.110…

It was recently reported that Africans experienced a sharp, severe bottleneck around 900kya and that this signal is absent in non-Africans. Here, we present evidence to show why this is likely a statistical artifact: Rasmus Nielsen Yun S. Song biorxiv.org/content/10.110… 1/4

In this preprint with Arun Durvasula, we discuss how there is no evidence for a bottleneck in the panmictic ancestral population of humans ~ 1 million years ago, as was suggested by Hu et al in Science last year biorxiv.org/content/10.110…

New work from my lab, led by graduate student Janis Liu. Janis studied type I error rates in Qst/Fst comparisons (1/n, link to preprint below)

My paper about type I error rates in Qst/Fst comparisons is now published in Genetics Society of America. Check it out here: academic.oup.com/genetics/advan…

James Lee and Damien Morris have an interesting perspective paper out describing "some far-reaching conclusions" about the genetics of intelligence. This type of "where are we now" paper is very fun and more people should write them! So, where are we now? 🧵