Had a lot of fun recalling fond memories from my undergrad for this interview. Excepting the endless staircases, I had such a fantastic time at Cal State San Marcos! thanks Eric Breier news.csusm.edu/chemistry-alum…

We are actively recruiting a postdoc interested in working on developing new chemical biology tools for protein interaction discovery. If interested, please email me at [email protected]! gerilab.weill.cornell.edu/team

We're hiring! We have several postdoc positions open for chemical biology research and proximity labeling in the MacMillan Lab. Experience in cell biology, biochemistry, molecular genetics, immunology, or related fields desired. DM us with your info and a CV/cover letter!

Excited to share this one. Great team effort.

Plus another Merck collaboration with MacMillan Group showcases how an additive screen can substantially broaden the scope of nickel/photoredox catalysis science.org/doi/10.1126/sc…

Using super-resolution microscopy, we provide some insight into the spatial selectivity (labeling radius) of proximity labeling technologies. We also developed some new ones along the way. pnas.org/doi/10.1073/pn…

Great collab between Alexander Ploss Princeton MolBio and MacMillan Group Princeton Chemistry, ID’ing 8 novel receptors for #COVID19 on the human cell, including 4 important for viral entry. Congrats to all. Story, link to J. Am. Chem. Soc. paper: bit.ly/3eRiTW2

lnkd.in/gPcXteFw lnkd.in/gbiRUDet

Check out this preprint on cubanes. Using a convenient approach to cyclobutadiene and copper photoredox catalysis, we are able to access bioisosteres of ortho-, meta-, and para-substituted benzenes for Med. Chem.   chemrxiv.org/engage/chemrxi…

TransitID is out today in Cell! This is a proximity labeling method for unbiased discovery of endogenous proteins that traffick from a defined “source” location to a defined “destination” location. TransitID uses sequential labeling by TurboID in the source, followed by a chase

What if small molecules could allow you to alter protein localization at will? What if they could allow you to turn on specific transcription factors? Our new manuscript reveals bifunctional molecules to do just that. 🧵

Very cool work mapping binding sites with amino acid precision! And it’s extra rewarding when I see people I know using FragPipe 🤗

The Geri Lab is recruiting postdoctoral scholars to develop photocatalytic proximity labeling and proteomics technologies. Chemical biologists and chemists who want to learn chemical biology are welcome! gerilab.weill.cornell.edu/team The view from our recently expanded NYC lab space:

In a major milestone for science, for medicine, and for patients, the world’s first CRISPR drug has been approved in the UK. “A new treatment for sickle-cell disease and transfusion-dependent β-thalassemia has been authorised by the Medicines and Healthcare products Regulatory

New year, new proximity labeling protocol! We can use red light to access trifluoromethyl carbenes from diazos for proximity labeling. Congrats to david crab and Stavros Kariofillis for a great paper in collaboration with Merck! pubs.acs.org/doi/10.1021/ja…

Our new proximity labeling technology is now published!! This new subgroup is doing some amazing work - more to come! nature.com/articles/s4155…

We're entering into a golden age in proximity labeling, and photocatalysis is a major new driver for uncovering biological mechanisms. Check out our review (Benito F Buksh Sean Huth Danielle Morgan ) of the latest developments out now in CellChemicalBiology!

Really nice work showcasing how tuning chemical reactivity can improve spatial resolution for proximity labeling. Super cool. Directed Evolution of APOX for Proximity Labeling Using Phenols with High Redox Potentials | ChemRxiv - go.shr.lc/43oDp7z