Why UVA? Why BME? That's what Jacob Gershon asked 5th year PhD student Katie Gorick in this #BME2019 wrap-up video! MORE: youtube.com/watch?v=hGy13I… UVA Engineering Price Lab @ University of Virginia

So cool!

the actual distribution of bean salads do not match the theoretical distribution of bean salads — there are many bean salads more to explore

Our work on creating de novo proteins with functional motifs (binding interfaces, active sites, etc) using deep learning is published! Since the preprint, we have improved the methods and added experimental validation! 1/8 science.org/doi/10.1126/sc…

DALL-E’s amazing images are popping up all over the web. That software uses something called a diffusion model, which is trained to remove noise from static until a clear picture is formed. Turns out diffusion models can design proteins too!

NEW PROTEINS JUST DROPPED!! Check out our new preprint diffusing over protein sequence space to generate seq-str pairs 🪩🧪🤠

Introducing RoseTTAFold2: Protein structure prediction AI that combines the best of AlphaFold2 and RoseTTAFold. Even without IPA and triangle attention, RF2 achieves comparable performance to AlphaFold2. biorxiv.org/content/10.110…

I’ve spent the last few weeks making Wiki Wall Street 📖📈! It’s the stock market game but for Wikipedia articles! You can buy and sell “stocks” of Wikipedia articles priced by their daily pageviews — join and play at the link below! wiki-wall-street.com

Absolutely thrilled to unveil my latest preprint!! This marks the finale of my PhD journey, and VAEs have been my constant companions throughout it all. Gratitude overflows for the incredible support from Minkyung Baek, Hahnbeom and Gyu Rie! Preprint here: biorxiv.org/content/10.110…

Tanks for the shoutout Katie Link !

Very excited to share RoseTTAFold All-Atom and RFdiffusion All-Atom, methods for structure prediction and design of biomolecular assemblies! biorxiv.org/content/10.110… 1/n

🥁 Our manuscript "Multistate and functional protein design using RoseTTAFold sequence space diffusion" is finally out Nature Biotechnology! 🧵b/c it's changed a LOT since preprint! New highlights: - High res structures - Conditionally caged peptides - Multistate design

BIG DAY for protein design and structure prediction!! It’s been an incredible experience working under David for the past few years 💻🧬🦠

I woke up to some exciting news this morning! For the FIRST time, research that I worked on was published in a journal. Huge thanks to Mohamad Abedi, DanPiraner, Majo Duran, Kole Roybal, and David Baker for including me in this exciting project! nature.com/articles/s4158…

Next Tuesday, 12/10 @ 4 pm EST, we'll have Sidney Lisanza Jacob Gershon Sam Tipps present "Multistate and functional protein design using RoseTTAFold sequence space diffusion" Read the paper: nature.com/articles/s4158… Sign up on our website to receive Zoom links via email!

Had fun exploring guidance for backbone designability within this latent framework, excited to chat more about guidance with experimental data GEMBio Workshop ICLR