Apply today to present your work and connect with future leaders in RNA biology: grc.org/rna-editing-gr… And don't forget to apply to the associated RNA Editing GRC following immediately after in the same venue for more cutting-edge science and networking! ✨

There are more ways to design an mRNA than atoms in the universe, so how do you choose the best one? Our new BASE mRNA Facility software, mRNArchitect enables you to tune expression, stability, reactogenicity and synthesisability to design more potent #mRNA drugs biorxiv.org/content/10.110…

Moderna’s first manufacturing site in the Southern Hemisphere has now officially launched here in the Monash Technology Precinct! monash.edu/news/articles/…

What an end to the year! Our work is out in Nucleic Acids Res! 🎉 We mapped #interactomes of both #ADAR1 isoforms during homeostasis & #interferon response. Thanks to the members of MOC group (Anna Cherian) at CEITEC and collaborators from Varjosalo_Lab! 🔗academic.oup.com/nar/article/do…

A new Science Immunology study reveals new pathways regulating the cellular response to unedited double-stranded RNA, which could underlie autoimmune conditions with ADAR mutations. scim.ag/3D0Ydag

Have you ever wondered whether pyroptotic corpses have functions beyond the grave? We made the surprising discovery that pyroptotic corpses are flagged by #filopodia to alert #DendriticCells they need autopsy. A short Tweetorial (1/13)👇with movies! Link: rdcu.be/d2mjm

We are excited to share pre-prints describing a successful foray into ML-driven protein design. With Rhys Grinter we designed proteins to potently inhibit CRISPR-Cas13 (doi.org/10.1101/2024.1…) or block heme piracy by pathogenic E. coli (doi.org/10.1101/2024.1…):

If you have a sec, check out our new paper by Amy Hsu with Hibbs Lab (Monash University STM Department of Immunology) and Ivana Hálová (Institute of Molecular Genetics) showing that CD53 drives cellular infiltration and inflammation in allergic airway asthma-like disease in Allergy EAACI (it's a quick read). doi.org/10.1111/all.16…

📢 New paper from the lab! In a fantastic new collaboration with Ana Tufegdžić Vidaković lab, we characterise a major Pol II homeostasis pathway in human cells. Congratulations Roberta @caciopporobi, Alex Alex Gillis, Ivan Ivan Shlamovitz, and Andrew. cell.com/molecular-cell…

Dear Everyone, I've read the #NHMRC draft strategy and I have notes ... So I'm going to...🧵🤔🧵😱🧵😵‍💫🧵🙏🧵🧵🧵 #NHMRCdraftStratergy #Ihavenotes #ValueFundamentalScience