'herd immunity' is really a bad idea. It might work fine if we were 200 years ago. But in modern time, this must be the job of science. It is likely in half a year, the jab will be available. Why cost us lots of lifelose to realise such 'herd immunity'.

Barley powdery mildew effector CSEP0162 targets multivesicular body-associated MON1 important for immunity disq.us/t/47g6rez

Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere biorxiv.org/content/10.110… Pleased to share our latest result in Barford Lab. Still lots to go! Very much enjoyed to work together.

We're proud of the major role we played in the discovery and development of the AKT inhibitor, capivasertib. Professor David Barford's team carried out the fundamental research to reveal AKT's #3D structure (below) and how it is activated. Read more: icr.ac.uk/news-features/…

Single molecule visualization of native centromeric nucleosome formation reveals coordinated deposition by kinetochore proteins and centromere DNA sequence biorxiv.org/cgi/content/sh… #bioRxiv

Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere biorxiv.org/content/10.110…

Mechanism of outer kinetochore assembly on microtubules and its regulation by mitotic error correction biorxiv.org/cgi/content/sh… #bioRxiv

Structure of the human outer kinetochore KMN network complex biorxiv.org/cgi/content/sh… #bioRxiv

Happy to share our work on the structure of the human outer kinetochore KMN network complex Many thanks to David Barford, Dom Bellini, Jing Yang and Ziguo Zhang for working with me on this project. biorxiv.org/content/10.110…

biorxiv.org/content/10.110… Our latest manuscript entitled "Assembly and phospho-regulatory mechanisms of the budding yeast outer kinetochore KMN complex".