A protocol paper was published in Methods in Molecular Biology "X-chromosome inactivation". link.springer.com/protocol/10.10…

BREAKING NEWS The 2018 #NobelPrize in Physiology or Medicine has been awarded jointly to James P. Allison and Tasuku Honjo “for their discovery of cancer therapy by inhibition of negative immune regulation.”

A structural view Of Pol II transcribing through The nucleosome #ChromatinHaiku #TxnJC science.sciencemag.org/content/early/…

Online now! New study uses adaptive light-sheet microscopy to establish a dynamic atlas of post-implantation mouse development at the single-cell level cell.com/cell/fulltext/…

We are excited to welcome Hiroshi, Yuko Yuko Sato , and Haruka from the Cell Biology Center at Tokyo Institute of Technology Hiroshi. They are the very first AIC visitors to use the new #SiMView with Autopilot instrument! #openscience #Janelia

Got HA-tag? Meet the HA frankenbody and check out our new preprint on imaging HA epitopes in vivo! biorxiv.org/content/early/…

Single-molecule imaging correlates decreasing nuclear volume with increasing TF-chromatin associations during zebrafish development @GebhardtLab Biophysics Ulm go.nature.com/2AYeAAw

Our chromatin integration labeling (ChIL) paper was finally published. The idea came up with Yasu Ohkawa 7 years ago, and the first positive data 4 years ago. nature.com/articles/s4155…

日本の修士在籍の学生さんへ EMBLのPhD programは給料もよいし素晴らしい研究室がたくさんありますよ。世界各国から応募がある中、日本からの応募がほとんどないのは正直寂しいので、よければ候補に入れてみて下さい。とかいう私自身はこの年になるまで一度たりとも留学経験なかったですけども。。

My first peprint is finally out. Thank you to all our collaborators!! disq.us/t/3df4xho

I had a great experience!

弊学のPhDプログラムの募集が始まりました。 GRE/TOFEL scoreは必要無し。 学費無し。給与は本年度$41,700。キャンパス内に格安ハウジングと保育所。TA必要なし。素晴らしい事務、IT、セキュリティスタッフ、コアファシリティが、研究に集中できる環境を作り出してくれています。是非トライを！

My paper is finally out! Visualization of active transcription and histone modification dynamics in living zebrafish embryo. Thanks for the collaboration! Nadine Vastenhouw Lennart Hilbert Vasily Zaburdaev 🇺🇦 @successprocess @OHaruka_TITech Hiroshi dev.biologists.org/content/146/19…

Transcription and histone modifications in live zebrafish embryos From Yuko Sato Lennart Hilbert @OHaruka_TITech Vasily Zaburdaev 🇺🇦 Nadine Vastenhouw @successprocess Hiroshi Kimura & colleagues Part of our Chromatin and Epigenetics Special Issue dev.biologists.org/content/146/19…

Our most-read paper in October was Yuko Sato, Hiroshi Kimura & colleagues' T&R applying Fab-based live endogenous modification labeling to monitor histone changes & transcription in zebrafish ZGA 🥂 dev.biologists.org/content/146/19…

今日が授賞式なのでもう一度。副賞を使って、日本の大学生をバルセロナの私のラボに招待します 実はこのキャンペーンの真の野望(?)は宣伝過程にあって、多くの学生さんに「海外大学院に進学かあ」とちらっとでも意識してもらうことです 拡散手伝っていただけると嬉しいです forms.gle/tN71pJn8HtzssZ…

12 days of #Devmas - Day 6 In October we published our Special Issue on Chromatin & Epigenetics - its most-read paper was Yuko Sato & colleagues' visualisation of histone modification and transcription during zebrafish ZGA dev.biologists.org/content/146/19…

Our lock-down baby is finally out ! Great story about heterochromatin, live imaging and X inactivation! Beautiful collaboration with Hiroshi Heard_Lab @SimoTeixeirada3 Yuko Sato | EMBO reports bit.ly/2Zs3ErL

Mintbody constructs for H4K20me1 and H3K27me3 are now available from Addgene. Enjoy live cell imaging of histone modifications. addgene.org/Hiroshi_Kimura/

🚨 Preprint alert 🚨 Excited to share our work on "Ab-trapping," an antibody artifact causing misleading peripheral ("rim") staining in imaging & genomics (IF, CUT&Tag, CUT&RUN). Antibodies fail to penetrate structures, accumulating at the periphery. A🧵👇 doi.org/10.1101/2025.0…