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Vahidi Lab@UofGuelph 🇨🇦 Chimerix, Inc. many congratulations, Siavash and the team! Looking forward to reading the preprint.

I am looking for a highly talented postdoc to join my lab to study ATP-dependent AAA machines using structural biology, biochemistry, and mass spectrometry. Please apply through the following link: bit.ly/4haSZID For more information, visit: sites.wustl.edu/ghanbarpour/

We must rapidly reverse our discovery research funding death spiral. Our future health and wealth depends on a well funded robust scientific research enterprise policyoptions.irpp.org/magazines/octo…. Brad Wouters 🇨🇦 CIHR NSERC / CRSNG André Picard Chrystia Freeland François-Philippe Champagne (FPC) 🇨🇦 Independent Senators Group (ISG)

Neuroscientists at #UofG are researching key enzymes in patients with Huntington’s disease, aiming to lay the groundwork for therapeutic treatment for patients with Huntington’s and other neurodegenerative disorders. College of Biological Science MCB at UofG Read more: news.uoguelph.ca/2024/10/neuros…

#OnTheBeamlines: Evidence links gum disease to heart diseases, cancer and Alzheimer's. A McGill University team has used our CLS to study how gum disease bacteria spread in the body to help develop new antimicrobial drugs one day. 🔬 bit.ly/3VwOaAB #synchrotron #science #health

Professor Lewis Kay Kay Lab University of Toronto is honoured with the 2025 Alexander Hollaender Award in Biophysics awarded by the U.S. National Academy of Sciences National Academy of Sciences for outstanding contributions to the field of biophysics utoronto.ca/celebrates/lew… #NMRnews #NMRchat #NMR 🧲

Thrilled to share our new paper revealing an auto-inhibited state of the M. tuberculosis 20S proteasome—highlighting allosteric sites with therapeutic potential. A fantastic collaboration with the Vahidi Lab@UofGuelph 🇨🇦! 🔗 nature.com/articles/s4146… #cryoEM #TBresearch #StructuralBiology

Mechanism of allosteric activation in human mitochondrial ClpP protease | PNAS pnas.org/doi/10.1073/pn…

Bit of a late post, but I had the incredible opportunity to attend and present my work at the Biophysical Society Annual Meeting this year! It was my first #BPS and also my first conference outside Canada. I got to learn from so many inspiring biophysicists doing amazing science!

New #UofG research may unlock better treatments for leukemia and tuberculosis, which affect millions worldwide. “If we can trap these enzymes, there is a chance we can make some very potent therapeutics," says Dr. Siavash Vahidi. College of Biological Science Read more: news.uoguelph.ca/2025/04/protei…

Credit to outstanding trainees and collaborators, including Natalie Zeytuni and Adwaith B Uday (he/him)

New findings from #UofG researchers could help unlock better treatments for leukaemia and tuberculosis. The studies focus on specialized enzymes that destroy damaged proteins and reveal how these enzymes can be switched on or off. Learn more: uoguel.ph/fxwpf

Congratulations to MSc MCB at UofG student Erin Rudolph, who came 2nd at the #UofG Three Minute Thesis finals for her presentation on Mast Cells: The Fire Alarm of Immunity!🔥

A fantastic lab and an excellent PI!

Excited to share our new publication with Vahidi Lab@UofGuelph 🇨🇦! We reveal how human mitochondrial ClpP is allosterically activated—even by inhibitors—unlocking new strategies to target ClpP in AML. pnas.org/doi/10.1073/pn…

Don’t miss the Ann Oaks Lecture in Biological Sciences, with Dr. Lewis Kay, professor of molecular genetics, biochemistry & chemistry University of Toronto 🗓️May 28 at 2 p.m. 📍ALEX 100 More info: uoguelph.ca/cbs/events/202…

Congrats to Monica Goncalves and Madison Turner for winning the 2025 Dr. Donald R. Phillips Molecular & Cellular Biology Scholarship! The award recognizes research excellence, academic achievement, and meaningful contributions to MCB. Congrats to their supervisor, Vahidi Lab@UofGuelph 🇨🇦!

Out in pnas today Showcasing the power of NMR! NMR and enzyme kinetics show USP7 enzyme transiently sampling a low-populated active state, and its disease-causing variant enhancing these dynamics pnas.org/doi/10.1073/pn… Stellar work by students Gabi Valles and Emilie Korchak