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Poll of the day Should patients with typical #MS lesions on MRI during the first attack be tested for the MOG-antibodies to rule out #MOGAD? #NeuroTwitter

Advocating for yourself or a loved one with a rare disease is important. Take charge of your #MOGAD care journey with these empowering steps. Learn more about MOGAD & The MOG Project community of support in the full infographic, developed in partnership with UCB:

A mid 20s relapsing #MOGAD pt comes into the clinic. Her clinical symptoms are: 1- VA 20/60 in L eye & 20/200 in R eye 2- Red/color desaturation 3- Pain with eye movement 4- Photophobia 5- Struggles to follow finger movements Based on her clinical symptoms, is this a relapse?

The thesis has landed! 🚀📚🎓 After years of rewrites, stats, and soul-searching, it’s finally real! Huge thanks to Sudarshini Ramanathan and co-supervisors Russell Dale, Fabienne Brilot & the MOG-dawggz! 🤘 #PhD #Neuroimmunology #MOGAD #AcademicTwitter University of Sydney DB Bookbinders The MOG Project

Guess what Australia & New Zealand. Thanks to Julia & Jenny Khazen, a zoom support group for #MOGAD pts is now up & running every month by Kathy, a MOG pt from Melbourne! With 100 pts in the ANZ MOGAD support group, this is a huge step & a very important milestone. Congratulations

Last week, 13 clinical #MOGAD relapses in the community both children & adults occurred with seronegative/low titre MOGAb. Majority of these relapses were ON or TM. These pts have confirmed MOGAD based on 1st presentation/criteria. Does the MOGAb still matter after diagnosis?

🚨 Action needed – RSVP today! Last month, we learned the MS Research Program would receive 0 funding in FY 2025 — a devastating blow to all who live with MS. Join us Tuesday, April 29 at 2 p.m. ET to help restore this critical funding. RSVP: ntlms.org/SaveTheMSRP

33 yo female with encephalopathy and visual impairement #neurorad #FOAMrad

Delighted to share our recent contribution led by Magdalena Lerch⁩ to a special edition of Seminars in Immunology! We take a deep dive into the pathogenesis of neurological immune related adverse events post immune checkpoint inhibitor therapy 🧠🧪 sciencedirect.com/science/articl…

If a young #MOGAD patient can’t stop relapsing with multiple treatments trialed, would you consider enrolling them in a clinical trial knowing they might receive the placebo arm? EDSS >2

Delighted to share Cacciaguerra et al study ➡️ MRI guidelines in MS recommend 2 sagittal-T2 spine images but axial is optional ➡️ Here, axial-T2 found 2x more lesions vs sagittal ➡️ Thus, future guidelines should recommend both sagittal & axial images👇 link.springer.com/article/10.100…

#multiplesclerosis versus #NMO versus #MOGAD

Which patients are more likely to have a relapsing course of #MOGAD? Those with:

A middle aged female was diagnosed with #MOGAD after a presentation of: Difficulty swallowing, hoarseness in her voice, droopy eyelid & double vision. Her MOGAb was 1:100 with no Demyelinating evidence on MRI Does this sound like typical MOGAD?

MOGAD: A comprehensive review of clinicoradiological features, therapy and outcomes in 4699 patients globally sciencedirect.com/science/articl…

Some clinicians internationally are giving #MOGAD women who’ve just given birth a small dose of RTX or IVIG to prevent relapses during the postpartum stage. Do you rate or hate this method?

Delighted to share Dinoto et al study on late onset MOGAD (50 yrs or more) ➡️ Accounts for 25% of MOGAD ➡️ Optic neuritis dominates & often misdiagnosed as ischemic (NAION or temporal arteritis) ➡️ Outcomes favorable & similar to other age groups 👇 neurology.org/doi/10.1212/WN…

A middle aged relapsing #MOGAD patient had x2 optic neuritis relapses with hearing loss on Rituximab. She was then put on IVIG after 5 doses of high IV steroids where she had another further relapse. What would be your next choice of treatment?

If you haven't already, mark your calendars! We're so excited to host the U.S. #MOGAD Patient Summit on Saturday, August 16th in collaboration with Mayo Clinic. Plan on learning the latest information on this disease, its diagnosis, management & treatment from the clinicians