From the June issue— Combinatorial BCL-2 Family Expression in Acute Myeloid #Leukemia #StemCells Predicts Clinical Response to #Azacitidine/#Venetoclax, by Alexander Waclawiczek, Aino-Maija Leppä, SimonRenders, Tim Sauer, HI-STEM - Cancer and Stem Cells in Heidelberg et al. bit.ly/3X7lOMo DKFZ

Delighted to share our new publication in @nature describing the first pharmacological approach that targets EMT, decreases metastasis and sensitizes cancer cells to chemotherapy in preclinical models of tumor with EMT nature.com/articles/s4158…

5 DAYS LEFT to register for the International Heidelberg Symposium on Stem Cells and Cancer on Sep 10-12 DKFZ . Explore cancer stem cells, tumor heterogeneity, tumor metabolism, therapy resistance, metastasis and more! Register now for FREE at stem-cells-cancer.de. #SCC2023

Fenia Fotopoulou from ⁦Experimental Hematology Lab⁩ doing a fantastic job of presenting her PhD project in the New Investigator Award Session of #ISEH2023 ⁦ISEH⁩ : couldn’t be prouder!!!!

Our latest study is out🥳🎉 check it here 👇🏻 big thanks to all our awesome collaborators that made this story possible :) also thanks for highlighting our work Hematopoiesis News! MPI of Immunobiology & Epigenetics

Andreas HI-STEM - Cancer and Stem Cells in Heidelberg DKFZ giving a great talk about complex karyotype AML and cancer neuron interactions at his home stage today at #SCC2023HD

Last day of our symposium on stem cells and cancer! Time to close this #SSC2023 with more great talks today. Thank you DKFZ for the hospitality. HI-STEM - Cancer and Stem Cells in Heidelberg and Dept. of Hematology, Oncology, Rheumatology UK-HD will join forces s again for #SSC2025

Thanks so much Beth Psaila for this nice summary in The Hematologist of the recent Cancer Discovery paper by HI-STEM - Cancer and Stem Cells in Heidelberg and colleagues aacrjournals.org/cancerdiscover…

Interested in the "Arms-Race" against therapy resistance in Acute Myeloid Leukemia? Read our perspective just published in molecular oncology. febs.onlinelibrary.wiley.com/doi/10.1002/18… HI-STEM - Cancer and Stem Cells in Heidelberg Aino-Maija Leppä SimonRenders

AML is an evasive, multi-arm(ed) foe that needs to be disarmed by continuous translational research efforts to increase treatment for our patients. Here we review recent results and highlight future directions. febs.onlinelibrary.wiley.com/doi/10.1002/18… HI-STEM - Cancer and Stem Cells in Heidelberg Aino-Maija Leppä Alexander Waclawiczek

💐Our March Issue is available to browse🌼 🐙Cover: An arms race against leukemia resistance 👀Have a sneak peek 👉buff.ly/3VcKunF #TherapyResistance #FASN #Glioblastoma #BCSM #LCSM #PDAC #CancerScreening

Less than 1 week left to apply for the #Staff #Scientist position in our group! Application via: lnkd.in/ePXJCJmv

Extremely proud to see my PhD project exploring intra-tumor heterogeneity in complex karyotype AML finally out in Nature Genetics ! 🎉👩🏻‍🔬 They say that 10,000 hours make you an expert, so I guess after more than five years of work I’m half-way there 😅 ⬇️1/5 nature.com/articles/s4158…

Now online - Article "Circulating tumor cell plasticity determines breast cancer therapy resistance via neuregulin 1–HER3 signaling" ✏️Roberto Würth & Andreas Trumpp and team DKFZ nature.com/articles/s4301…

Pancreatic #cancer is fueled by connections to the nervous system. Scientists from DKFZ & HI-STEM - Cancer and Stem Cells in Heidelberg discovered that blocking nerve function inhibited cancer growth and increased the sensitivity of tumor cells to certain therapies. nature ➡️ t1p.de/j51g0

Today @nature How pancreatic cancer can hijack our nervous system and that denervation may be therapeutic nature.com/articles/s4158…

🚨 Paper out in Nature 🚨 Amazing news from the Trumpp Lab @HI_STEM_lab performed by Vera Thiel VeraT, Simon Renders SimonRenders and Jasper Panten! Discover how tumors interact with nerve cells! 👇👇👇  nature.com/articles/s4158… #CancerResearch #Neuroscience

Nature research paper: Hepatic stellate cells control liver zonation, size and functions via R-spondin 3 go.nature.com/41QxyFE