What a week! Thanks Louis Kuemmerle and Fabian Theis for the invitation and for such an amazing hackathon full of interesting discussions in a lovely place #spatialomics #computationalbiology.

1/n Single-cell data analysis is complex with many tools to choose from - but which ones work best and should be used when? Led by @lukasheumos and @AnnaCSchaar, we wrote a free online book that aims to guide single-cell data analysts: sc-best-practices.org

🔥off the press, our new study with MatsNilssonLab is online! Very proud of this work led by fearless and fabulous Ilon Liu, Li Jiang and Erik Samuelsson on the spatial organization of adult and pediatric H3K27M gliomas. Dana-Farber/Boston Children's Karolinska Institutet nature.com/articles/s4158…

Great work from both Erik and Sergio Marco from the lab and collaborators Mariella Filbin Ilon Liu ! A fantastic use of #InSituSequencing to profile the spatial organisation of diffuse midline #glioma. 🔥🔥🔥🔥🔥🔥

A rare incurable cancer has been visualized for the first time by an international team of researchers, co-led by SciLifeLab researcher and Spatial and Single Cell Biology platform Director MatsNilssonLab (Stockholms universitet). Read more: scilifelab.se/news/new-metho…

Out in Nature Cell Biology! In collab with Samakovlis lab, Alexandros Sountoulidis & Sergio Marco built a #spatiotemporal atlas of the human embryonic lung. Novel cell types, differentiation trajectories & interactions identified. Want to know more? See #Thread 1/N nature.com/articles/s4155…

Excited to share our new paper in Cell! We unveil what makes skull cells unique compared to other bones and explore the skull's intricate response to brain disease. I am grateful for everyone involved that made this work possible, first and foremost Ilgın Kolabas and Ali Max Erturk!

This is our humble attempt to democratize in situ transcriptomics for the masses. Here in this preprint, we MatsNilssonLab have put together an end to end solution for targeted in situ transcriptomics that is compatible with immunostaining and other labelling methods. ... 1/N

🚨New preprint🚨 Who says spatially resolved transcriptomics solutions need to be extremely expensive 😤? We say, it does not have to be *that* complicated nor expensive. biorxiv.org/content/10.110… Hower Lee Christoffer Langseth Sergio Marco Marco Pariggiano

Hello World! 🌍 Exciting news: We've just launched spatial.ist_papers, your go-to source for intriguing spatial biology articles. 🧬As part of spatialist, we aim to empower scientists by spotlighting the wonders of #SpatialBiology. Join us on this scientific journey!

Petra Kukanja & Christoffer Langseth et al. tour-de-force it is now out in Cell Cell! An one-of-a-kind collaboration with MatsNilssonLab, powered by the fantastic in situ sequencing technology Mats pioneered! Check it out at sciencedirect.com/science/articl…

Super cool work from Eneritz Fernando García-Moreno on the evolutionary convergence of sensory circuits! Perfect example on how to use #scRNAseq and #insitusequencing #spatialomics in the context of #EvoDevo. Very fun collaboration!

We are delighted to present our newest research tool, BirthSeq, in @Development! Now you can sequence, locate and analyze cells according to their embryonic birthdate. This method was tested in birds 🐣🐁and mice, and its potentially useful in any vertebrate species and organs!

🔎Interneuronal divesity in the human striatum uncovered!🧠 We are glad to contribute to the spatially-resolved characterization of striatum in an effort lead by Ana Munoz-Manchado and her team👩‍🔬 #spatialbiology #xenium

Our pre-print "Comparative evaluation of methods for the prediction of protein-ligand binding sites" is out on Research Square. Check it out! 🔗 tinyurl.com/Utges-LBS-comp On this paper we benchmark 11 ligand binding site prediction tools on our curated reference dataset: LIGYSIS!

We have mapped the adult human lung by combining multiple #spatialomics technologies, describing clear regional variability. A collaboration lead by Alexandra Firsova from the Samakovlis lab in the context of discovAIR. Check our preprint! researchsquare.com/article/rs-504…

Conducted by @RuedaEneritz, we have seen that pallial neurons are generated in different regions and stages of the embryonic brain🐣🦎🐀: pallial neurons and circuits have evolved separately. Evolutionary CONVERGENCE of neurons and circuits! shorturl.at/PlWGR

🧬Working in #spatialbiology? This might interest you! In our new publication we have done a deep exploration 🔎 of 10x Genomics Xenium data, comparing it to other platforms and defining best analysis practices. Out now in in Nature Methods nature.com/articles/s4159…