
Sanghyun Lee
@sanghyunleelab
The Lee Lab @BrownUniversity studying novel Host-Virus interactions in cells and animals
ID: 1164269927542460417
https://sites.brown.edu/leelab/ 21-08-2019 20:16:08
39 Tweet
177 Takipçi
99 Takip Edilen


Great work by Craig Wilen on norovirus cell tropism. It was my pleasure to contribute a small part of it.





The first annual CONVICTIONS symposia. Great sharing science with old and new friends with Wilen and Sanghyun Lee. Also, great post-meeting Providence river cruise.Yale Lab Medicine Brown University



Our new preprint is out today. We found that human LRRC15 is an inhibitory receptor for SARS-CoV-2 spike-mediated entry. LRRC15 directly binds to the RBD of spike and inhibits viral entry in trans. Thanks for wonderful collaboration with Craig Wilen biorxiv.org/content/10.110…

Happy to share new paper by awesome postdoc Andrew H Kim from great collaboration with handleylab and Vanessa Harris, looking at bacteriome and virome associations with vaccine responses: authors.elsevier.com/sd/article/S19…


Norovirus cell tropism: The road to uncovering its secret hideout Sanghyun Lee cell.com/cell-host-micr…




It is published! This is our first peer-reviewed publication in the Lee Lab with wonderful collaboration with Craig Wilen. LRRC15 as novel cellular entry inhibitor of SARS-CoV-2.

Second annual CONVICTIONS symposium was a terrific success! Great reuniting with the Sanghyun Lee and sharing science! Yale Lab Medicine


How is norovirus infection in tuft cells controlled? A collaboration work with Craig Wilen shows short-lived tuft cells are the reservoir. Tuft-cell-intrinsic + extrinsic IFN-I & -III control norovirus in the gut. Now published in Cell Reports