2018 and 2020 GRS Centromere Biology Chairs! #GRCentromere Leah Bury Owen Smith Samuel Corless

Check out our newest review paper!

Biophysics question: In transcription, RNApol generates positive supercoils ahead of it and negative ones behind it WHY? Why doesn’t RNApol instead simply track 1 strand of the duplex, follow its helical twist along the duplex, and thus rotate without any supercoil generation?

New research in Science presents a synapse-by-synapse map of an insect’s brain, representing a valuable resource for future experimental and theoretical studies of neural circuits and brain function. scim.ag/1RU

The bromodomain inhibitor JQ1 is a molecular glue targeting centromeres biorxiv.org/cgi/content/sh… #bioRxiv

Thanks chromatin community! We’ve been digging around in your repetitive DNA (>40,000 ChIP-seq samples) and have discovered a totally unexpected role for BRD4 and JQ1 at centromeres. Very happy to share our preprint. biorxiv.org/content/10.110…

Did you know JQ1 directly targets BRD4 at centromeres? #Epigenetics is more than gene regulation! To find out more read our updated BioRxiv biorxiv.org/content/10.110…

This study is amazing! I always wondered if the role of nucleosomes was more about DNA supercoils than 'packaging', these different topologies are a nice hint in that direction. biorxiv.org/content/10.110…

Centromere biologists take note!

a while ago I posed this question... 1/

Several roadblocks must be overcome to make molecular biology more sustainable, but Martin Farley UCL argues that we must treat sustainability like we do health and safety in the lab—as a necessity.

Warm welcome to our new Principal Investigator Dr Nezha Benabdallah @NsBenab👍! Nezha leads the Chromatin Regulators in Cancer research group. Her scientific interests focus on sarcoma research and chromatin biology. Read more on our website: ed.ac.uk/cancer-centre/…

Calling all aspiring centromere biologists! Rae Brown (Straight Lab) and I will co-chair the GRS for Centromere Biology, preceding the main GRC on 27th-28th July 2024. Please retweet and register before April 21st to be considered for a talk! grc.org/centromere-bio…

Join us at our 22nd EdinburghEpigenetics Meeting The University of Edinburgh Network #research #epigenetics #chromatin #Edinburgh