Du et al. identify a mechanism by which glucocorticoid stress hormones induce mitochondrial damage and tau pathology in mice, and show that targeting mitochondria may be a promising strategy for reducing stress-related neurotoxicity. bit.ly/3AjGxSB

New priprint from the lab, describes the presence of a small peptide-mediated wound signaling cascade involving Phytosulfokine and its receptor. Aimed at answering how many monocots tend to shrug off mechanical wounds. Fantastic effort led by Harshith biorxiv.org/content/10.110…

Clinical and translational neuroscience research in Autism: Challenges and Strengths, with a Focus on ElectrophysiologyGet ready! INSAR Institute 2023 starts next Thursday, don't forget to register to receive the Zoom link to join in: autism-insar.org/page/Institute…

We are glad to have been represented at the International Psychogeriatric Association International Congress, Lisbon. It was an excellent platform to discuss findings on the association between social networks & cognitive functions in our #SANSCOG cohort. IPA kris gopalakrishnan

Our new Molecular Cell paper reveals that #mRNA stability takes the lead in mRNA localization. Congrats to Inga Loedige Artem Baranovskii Samantha Mendonsa, Laura Breimann Stefan L Ameres & co-authors! 🎉 MDC-BIMSB Max Delbrück Center Max Perutz Labs Vienna chekulaevalab.org/2023/07/13/sta… sciencedirect.com/science/articl…

Finally!!! Tuning ribosomes and cell differentiation with one single methylation - check out our latest publication from @therealLundLab : authors.elsevier.com/c/1hRk85Sx5gtw…

We are delighted that our faculty member Bratati Kahali has been recommended for the IA Intermediate Fellowship, which will help harness the power of large-scale #genetic analyses to study the interplay between metabolic risk factors and cognition to gain insights into #dementia.

We are proud to share that Dr Justin Joseph, a postdoc in the lab of Chinnakkaruppan Adaikkan, has been recommended for the DBT/WT India Alliance Early Career Fellowship. His project is aimed at developing & optimising a brain-computer interface to modulate neural activity in #Alzheimersdisease

Curious to know more about cell-cell transfer through Tunneling nanotubes and their effect on alpha- synuclein induced toxicity? Check out the link in the thread PhD Voice - Independently Run Academic Chatter™ OpenAcademics The PhD Place PhD_Genie #AcademicTwitter

Happy to share our new article on the #CACNA1A variant from our group. authors.elsevier.com/sd/article/S18… #Freudegroup #epilepsy #CACNA1A #epilepsyeducation

New paper from Cytoskeleton Lab Drisya Dileep Aamy in collaboration with Tabish Syed, Kaleem Siddiqi McGill University Tyler Sloan Dhandapany Perundurai embopress.org/doi/full/10.15… We combine tissue clearing, volumetric imaging & computer vision to obtain micron-scale heart myofiber organization

Happy to host postdocs in our group--we work on genetics of Indian populations in the context of aging and neurodegeneration. Please reach out if interested!

A potential therapeutic target for ASD: downregulation of histone acetylation (could be a signature of SYNGAP1-related asd #autism #brain #drug #disease #therapy biorxiv.org/content/10.110…

This work highlights the different calcium channels involved in controlling protein synthesis in neurons, and shows the dysfunction of this process in Alzheimer's disease neurons Centre for Brain Research, IISc Ravi Muddashetty Lab Sarayu Ramakrishna bit.ly/3ylYfal

Excited to share our current findings published in LifeScienceAlliance ! Congratulations to Sarayu Ramakrishna , Bindushree and Nisa. Well deserved!

See our latest publication by Abinaya Raghavan cell.com/iscience/fullt… on how neurodegenerative stress facilitates toxic materials sharing with neighbours through membrane nanotubes. It is a product of great collaboration efforts. Thanks to Sivaraman Padavattan Ravi Manjithaya Ravi Muddashetty Lab.

Delighted to share our latest preprint led by Michelle D'Souza and Naveen Gowda which reveals FMRP's role in regulating rRNA 2’O-methylation during neuronal differentiation, impacting ribosome function and protein synthesis. Dasaradhi Palakodeti Ravi Muddashetty Lab biorxiv.org/content/10.110…

The No Garland Neuroscience Meeting is back! Join us IISER Thiruvananthapuram from December 5-8, 2024. Follow NGN 2024 for regular updates! 🧠 Register & submit your abstracts now. Amrutha Swaminathan & I can't wait to welcome all #neuroscience enthusiasts to our campus. ngn2024.wixsite.com/iisertvm

Transcriptome-wide mapping of small ribosomal subunits elucidates scanning mechanisms of translation initiation in the mammalian brain biorxiv.org/cgi/content/sh… #biorxiv_neursci

HIRING JRF! Join our team at CBR for a project on 'Mitochondrial translation dysregulation in Alzheimer’s Disease.' Send your CV and two references to [email protected] by August 8, 2025. #Alzheimers #JRFHiring #Mitochondria