🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Want to work in early cancer detection using machine learning on multi-omic data? Look at link below - great opportunity with the brilliant Paul Yousefi, caroline relton, Matt Suderman, funded by Science and Innovation at Cancer Research UK & embedded in MRC IEU ICEP Bristol Cancer University of Bristol

Amazing MRC funded PhD project to exploit genomic data using big data to understand mechanisms behind the prevention of several cancers by physical activity gw4biomed.ac.uk/investigating-… Led by John Campbell, Bath, collaborating with Bristol Cancer ICEP funded GW4 BioMed MRC DTP | @gw4biomeddtp.bsky.social

Antonis Antoniou presenting his ambitious vision for data enabled cancer detection, prevention and diagnosis! Major initiative from Science and Innovation at Cancer Research UK & really excited to be involved. Lovely setting too. #CD3Workshop23 ICEP Bristol Cancer

If you’re a mixed methods health services researcher with interest in cancer prevention this NIHR Bristol Biomedical Research Centre (BRC) may be just the post for you! Involves great collaboration with colleagues at Bradford Institute of Health Research. jobs.ac.uk/job/DCT601/sen… ICEP Bristol Cancer

I love my sisters art Gio Martin and love when she sends me her work as a present! This one’s another gem, arrived today! Thanks sis!

We’re advertising a really interesting post MRC IEU analysing protein biomarkers in cancer detection! If you have a background in genetic epi & are interested in risk prediction tools for the clinic, look up: jobs.ac.uk/job/DCV046/sen… Science and Innovation at Cancer Research UK ICEP Philip Haycock 🎗

Fantastic opportunity for 5 new PhD students to join us at Bristol MRC IEU Bristol Mol-Gen PhD ICEP Richard Martin.Open to Home and International students with various project titles. Closing date: 6th December 2023. findaphd.com/phds/program/w…

Delighted to announce a new fellowship in #mentalhealth in children and young people. With support from Prudence Trust, Elizabeth Blackwell Institute and @Bristolalumni have funded Laura Hull to research ways to support neurodivergent young people who camouflage.

Congrats Laura Hull on your award of a Prudence Trust/Elizabeth Blackwell Institute Fellowship to learn about neurodivergent young people’s mental health. Really looking forward to learning more about your important and novel research Elizabeth Blackwell Institute Bristol Population Health Science Institute

We have an exciting Senior Research Associate post using #genetics to⬆️#cancer early detection MRC IEU. Hybrid/remote working options. PhD or MSc w/ gen epi experience req'd. Closes 21 Dec Philip Haycock 🎗 @Karl_SmithByrne. Get in touch if interested! Pls retweet🙏shorturl.at/nrM79

🆕project from our diet and physical activity theme! Exploring drug targets to treat + prevent cancer. The team is working on finding new + repurposing existing drugs by first identifying #cancer-linked proteins to target Led by Richard Martin Project page tinyurl.com/548bfx3j

Compared with no invitation for routine PSA testing, a single invitation for a PSA screening test reduced prostate cancer mortality at a median follow-up of 15 years, but the absolute mortality benefit was small. ja.ma/43J43q3 #EAU24

The median 15 year results from Science and Innovation at Cancer Research UK funded trial of screening for #prostatecancer with a PSA test are published today in JAMA University of Bristol Health Sciences at the University of Bristol Richard Martin

In this preliminary report from an ongoing clinical trial, a screening protocol—PSA test, a kallikrein panel risk score & MRI before targeted biopsy—detected 1 high-grade prostate cancer per 196 men and 1 low-grade prostate cancer per 909 men. ja.ma/3TO5gry #EAU24

Editorial by Jeffrey Tosoian Jeff Tosoian, MD, MPH, David Penson Dave Penson, and Michigan Pathology Arul Chinnaiyan: A Pragmatic Approach to Prostate Cancer Screening ja.ma/3J7tlEK #EAU24

2. Granted MRI and other reflex tests reduce over-diagnosis (and the Ix related morbidity) but is it going to change the lack of OS gain seen here? and how would another test instead of PSA achieve anything better in terms of OS? or much more in terms of PCM?

Freddie Hamdy & Richard Martin introduce 15yr f/u to #CAP_Study => now see small difference 0.7% vs 0.8% PCa death p=0.02 Need to screen 1000 men to save 1 life from PCa PCa mortality <1% at 15yrs... (20% all cause) #EAU24 European Association of Urology (EAU)

Results from the largest trial to date on #ProstateCancer screening shows it has a small impact on reducing deaths but raises concerns of overdiagnosis.🔬 The Cancer Research UK CAPTrial Rob Martin & University of Oxford Cambridge University followed over 400,000 men over 15 yrs➡️brnw.ch/21wIzfZ

This is like before and after, but presented at the same time. Basic question (i) will any model of prostate screening alter OS to justify cost & resources needed (ii) if OS not endpoint, will we swap ⬇️morbidity from metastasis with⬆️tx related side effects for a small ⬇️in PCM

Thanks Tyler Seibert MD PhD yes, a truly remarkable team! Thanks for your involvement