I'm working towards making a blue lima bean. Along the way, I made the bright yellow one here.

Has anyone tried just asking the DNA nicely?

Another month, another insane protein design paper from the Baker Lab. This time: Designing binders for intrinsically disordered regions, a common & important component of proteins we care about, with the help of a diffusion model In nature last week

MOON CHEESE 🌕 🧀

home automation in poland is wild

True Biopunk

You thought systemd was bloat? You're running genetic code that needs to build lizard hands before making human hands because of 250M years old technical debt

Everyone thinks biotech is being held back bc of funding, or because it’s complicated but actually it’s because we don’t have enough analog switches and buttons.

The future of mankind

CRISPR came from yogurt bacteria. GLP-1s came from Gila monster venom. Taq polymerase came from hot spring bacteria. As much as we like to think that progress in biotech is driven by human design, our biggest breakthroughs over the years have all originated from nature.

I’ve gone slightly manic with the fermenting, today adding mango habanero hot sauce and fire cider to the mead, ginger bug, apple cider vinegar and kimchi I’ve already made. Soon I will be able to ferment even greater things like oak trees and Germans.

BREAKING: Sugars essential for life have been found in pristine asteroid Bennu samples collected by NASA’s OSIRIS-REx spacecraft. Combined with previous detections of amino acids and nucleobases, we see that life’s ingredients were widespread throughout the solar system:

RNA world hypothesis looking more likely