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🔉Out today in Communications Biology - our genomic analysis of earliest H58 S. Typhi organisms isolated from returning travellers to the UK suggests this highly successful lineage emerged in 1987 in India, likely from a chronic carrier, and was already MDR. nature.com/articles/s4200…

The ability of H58 to acquire & maintain AMR genes continues to pose a threat, as the emergence and spread of #XDR typhoid in Pakistan has demonstrated. Continued & expanded 🧬surveillance is needed to inform #TCV introduction and measure its impact #VaccinesWork

Salmonella typhi H58 likely emerged from a chronic carrier in India before spreading globally as investigated by isolates from travelers to UK between 1980 and 1995 Megan Carey To Nguyen Zoe Anne Dyson Satheesh Nair Marie Anne Chattaway doi.org/10.1038/s42003…

New research article Pathogen diversity and antimicrobial resistance transmission of #Salmonella enterica serovars Typhi and Paratyphi A in Bangladesh, Nepal, and Malawi: a genomic epidemiological study thelancet.com/journals/lanmi… #AMR #typhoid #OpenAccess #OA

NEW: A recently published genomics study looks at drug resistant #typhoid in #Bangladesh, #Nepal, and #Malawi🦠 sciencedirect.com/science/articl… The Lancet Microbe Zoe Anne Dyson James Meiring #TakeOnTyphoid

How can these findings help to #TakeOnTyphoid? Data found drug resistant transmission and patterns, highlighting the importance for decision-makers to take strategic action to protect communities! #Typhoid conjugate #VaccinesWork to protect against drug resistant strains💉

Great to see so many long term colleagues and friends on this paper. I remember the origins of STRATAA at the Wellcome. Came after we pointed out a gap and an opportunity. It has delivered.

Lovely work from the STRATAA consortium, led by Zoe Anne Dyson Ashton & @DrKatHolt. Consistent community surveillance in Africa and Asia dissected the behaviour of highly localised clusters of S. Typhi w/ AMR spreading between age groups and lasting over several seasons.

New research alert 🔔 A study in The Lancet Microbe by Zoe Anne Dyson reveals high levels of drug-resistant typhoid in Bangladesh, Nepal, and Malawi. Calls for increased focus on vaccination and WASH to combat this public health threat. Read more👇 bit.ly/45X8mz0

New preprint from TyphiNET! Typhi Mykrobe: fast and accurate lineage identification and antimicrobial resistance genotyping directly from sequence reads for the typhoid fever agent Salmonella Typhi biorxiv.org/content/10.110…

Also out this week: multiparameter #evolution training of #phage to target #Pseudomonas for improved cocktails in #phagetherapy. #publication in Nature Communications with Kunisch etal: nature.com/articles/s4146… #microbiology #bacteria

🗣️ Kicking off the #AMRDataSymposium with opening remarks from our Co-Directors, Gwen Knight & @DrKatHolt , as they set the stage for a day of discussions on the power of data in combating #AMR. Stay tuned for valuable insights!

Data & Statistical Science for Health, LSHTM Janet Midega Cherry Lim MRC Unit The Gambia at LSHTM London School of Hygiene & Tropical Medicine 🧩 Zoe Anne Dyson is chairing the flash talks on AMR data tools! 💡 Speakers are showcasing innovative tools and methodologies that enhance #AMR data collection and analysis. #AMRDataSymposium

Data & Statistical Science for Health, LSHTM Janet Midega Cherry Lim MRC Unit The Gambia at LSHTM London School of Hygiene & Tropical Medicine Zoe Anne Dyson LSHTM Research Data Dana Itani Saffie Darboe Still at the #AMRDataSymposium, Megan Carey is leading the panel discussion titled, ‘How We Share #AMR Data Nationally & Internationally.’ 🤝 Experts are exploring solutions to enhance collaboration and transparency in data sharing.

Data & Statistical Science for Health, LSHTM Janet Midega Cherry Lim MRC Unit The Gambia at LSHTM London School of Hygiene & Tropical Medicine Zoe Anne Dyson LSHTM Research Data Dana Itani Saffie Darboe Megan Carey Africa CDC UK Health Security Agency 🇮🇳 Kamini Walia PhD, MPH alan christoffels Barney McManigal The GRAM Project, Oxford 📢 Wrapping up the #AMRDataSymposium with our final panel discussion: “AMR Data for Policy—AMR Data to Support Global AMR Policy.” Experts are highlighting how data-driven insights can shape effective policies and drive global action against #AMR. 🌍

WHO study lists top endemic pathogens for which new vaccines are urgently needed ⁦World Health Organization (WHO)⁩ who.int/news/item/05-1…

📣 🎉 Congratulations to Gladys Maria Pangga and Zoe Anne Dyson on winning our 2025 Publication Prize at London School of Hygiene & Tropical Medicine 🏆 Read more about their winning papers and impactful AMR research🔬 👇 bit.ly/4iM7uCh

Zoe Anne Dyson won the Staff Prize for her work revealing that most AMR typhoid infections in Bangladesh, Nepal, and Malawi are driven by ongoing local transmission of existing resistant strains—not new variants.

📰 New publication! Read up on the TyphiNET data visualisation dashboard in Genome Medicine. The dashboard provides an interactive platform for accessing genome-derived data on pathogen variant frequencies to inform #typhoid control and intervention strategies. #TakeOnTyphoid