#Cellpose 3! Not all images are perfect. Restore your images with Cellpose3 to get better segmentations, w/ Marius Pachitariu biorxiv.org/content/10.110…

Our (news&) views on new monomeric StayGold variants can be accessed here: rdcu.be/dBbnS I hope you enjoy reading it!

Insane! My favourite figure, 21 targets labeled in one image! Multiplexing is now offered with 3 flavours: Optoplex, Enziplex and Chemiplex, relatively easy to adapt at your labs. Great work!

Danielle Beckman @dava_keavney Natalia Quinones-Olvera Like, come tf on BioRender biorender.com/academic-licen…

After countless requests, we're thrilled to introduce PK Mito Orange FX - a fixable variant of PKMO. PKMO FX allows immunolabeling and CLEM approaches. Happy to have contributed to this project led by Zhixing Chen and Christian Jüngst. #mitochondria pnas.org/doi/10.1073/pn…

Exciting preprint from the awesome folks (Mavrakis & Brasselet group) at Institut Fresnel on new fluorescent reporters that will allow for polarisation measurements (in addition to regular microscopy) of actin dynamics in live cells!This is a big deal! biorxiv.org/content/10.110…

The new mitochondrial probe PKmito ORANGE FX in now available! ✅ Optimized for PFA or GA fixed cell mitochondria imaging ✅ Highly suited for STED imaging ✅ Compatible with immunostaining and CLEM spirochrome.com/product/pkmito… Order it now from our distributors and take advantage

We present: 'Multispectral live-cell imaging with uncompromised spatiotemporal resolution'. biorxiv.org/content/10.110… 1/16

(1/x) We are excited to introduce VIPS (Volumetric Imaging of biological specimens via Photochemical Sectioning) in our preprint! VIPS uses a light-based process called “photochemical sectioning” to achieve petabyte-scale high/super-resolution imaging: biorxiv.org/content/10.110…

Scientific colour maps: yes!—But when and what not to do with them? 👉doi.org/10.1002/cpz1.1… including resources for researchers, science communicators, software developers, publishing editors, and University faculty! Dr Grace Shephard Philip Heron #DataVisualisation #UseBatlow

BioRender updated their terms and, oh yes, I'm sure journals will be *thrilled* to print hyperlinks direct to BioRender's website at the bottom of figure legends. help.biorender.com/hc/en-gb/artic…

Long awaited (thanks James Manton for posting the patent application!) and now out in Science Magazine: Using absorption to look deeper by HongLab - they achieved approx. 3 mm depth using the food dye tartrazine: #Microscopy science.org/doi/10.1126/sc…

Out at Nature Methods just now! nature.com/articles/s4159… We present #SN2N, a flagship level unsupervised denoising solution. It’s fully competitive with supervised learning without needing large training-set and clean ground-truth, using 1 noisy frame for training. (1/n)

Let me introduce: InstanSeg 🦠🔬💻👩‍🔬 This *would* have been a short thread about Thibaut Goldsborough’s PhD work… but he solved too many problems. Now it's a long thread about 2 preprints, a whole new approach to cell segmentation & #opensource software to make it easy to use

We developed a new super-stable RFP for advanced microscopy, like CLEM, Rapid tissue clearing, Live 3D-SIM and live STED. Read this #preprint on Research Square: mYongHong: a structure-guided design of stable and monomeric red fluorescent protein researchsquare.com/article/rs-471…

Which monomeric GFP is the brightest and most photostable? A winner has just been announced, and it is mStayGold from the Miyawaki lab, edging out two other monomeric StayGold candidates. biorxiv.org/content/10.110…

Pleased to present our latest work, where we show that the cell-cell adhesion protein afadin coopts mechanically-regulated elements of the cadherin-catenin complex to drive cytoskeletal engagement. biorxiv.org/content/10.110…

Happy to share my cofirst-authorship in this work about my phD project👩🏻‍🔬. We developed new reversible reporters to detect the dynamics of #MembraneContactSites and their associated #calciumsignaling. Enjoy your read ⤵️ and our colourful pics & movies🎦. nature.com/articles/s4146…

Apply to be the manager of a light microscopy core at Penn State College of Medicine in Hershey! psu.wd1.myworkdayjobs.com/PSU_Staff/job/…

Excited to share our new pre-print showcasing tools (chemical & optogenetic) for repositioning #vimentin in cells! Movie shows #ER (Halo-KDEL) sheets being relocalized together with vimentin (Vim) upon local vimentin pulling in U2OS. Gijsje Koenderink biorxiv.org/content/10.110…