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doi.org/10.1021/acs.jc… Out now in JCTC!! Very proud of @RajeswariAppad1 for this wonderful effort!! And loved the collaboration with Paul Robustelli JayaKrishna and Max Bonomi Also, thanks to IISc Bangalore, National Supercomputing Mission DSTIndia Department of Biotechnology for ₹₹

Very happy to share our study uncovering the mechanism of DNA binding by an IDP! The disordered domain of CytR binds DNA through a fully folded minor conformation. Athi N Naganathan @BODHISATWANANDI Molecular Biophysics Unit, IISc science.org/doi/10.1126/sc…

Excited to announce the publication of our study on the architecture of the ratGAT1 in the cytosol-facing, GABA bound state NatureStructMolBiol. Brilliant effort Smruti Ranjan Nayak and well supported by @DeepthiJoseph Archishman Dakua @AthreyaArunabh nature.com/articles/s4159…

Its a pleasure to announce the publication of our latest work on the cryoEM structure of QacA resolved using Indian camelid antibodies in The EMBO Journal . Fantastic effort by Puja Majumder shahbaz ahmed Pragya and @Athreya_Arunabh.embopress.org/doi/full/10.15…

Finally our research on thioamide modification and its implications in membrane permeability and bioavailability of cyclic peptides is out! Congratulations to the entire team! nature.com/articles/s4146… @hiteshvrm Bhavesh Khatri Nishant Raj Sohini (she/her) Molecular Biophysics Unit, IISc

Very happy to share our recent study on characterization and comparison of permanent and transient intra-protein inter-domain interactions. doi.org/10.1002/prot.2…

We are organizing our annual symposium, "NuBS23," tomorrow from 9 AM onwards at the Faculty Hall, IISc Main Building. Please join us to learn about our latest works and hear from our plenary speakers, Giriraj Sahu and sufyan.

jbc.org/article/S0021-… Out now in Journal of Biological Chemistry. Had a wonderful time working with Shovamayee Maharana and Sangeetha, who did all the heavy lifting !! Would like to acknowledge DBT/WT India Alliance, NSM (HPC grant DSTIndia) @SankhyaSutraLab Department of Biotechnology IISc Bangalore Molecular Biophysics Unit, IISc

Our recent work "The alteration of structural network upon transient association between proteins studied using graph theory" is out now in Protein: Structure Function and Bioinformatics Wiley Biomedical Science doi.org/10.1002/prot.2… Himani Tandon R Sowdhamini Molecular Biophysics Unit, IISc IISc Bangalore

#glycotime Out now in GLYCOBIOLOGY! Very chuffed to see this out as it's our first Glycan work !!! doi.org/10.1093/glycob… Thanks to Ramray Bhat Ramaswamy S Aravind Penmatsa for discussions and insights! Also, thanks to not here anymore & Glycobiology.UK for the smooth editorial process.

Our work on the "Comparison of structural networks across homologous proteins" is out in PROTEINS: Structure, Function, and Bioinformatics | Wiley Online Journal Wiley Biomedical Science onlinelibrary.wiley.com/doi/abs/10.100… Molecular Biophysics Unit, IISc

We are excited to start the new year by sharing the latest paper from our lab @MBU_IISC, IISc Bangalore in Nucleic Acids Res. Here, we report that the RTEL1 helicase interacts directly and functionally with the replication protein A (RPA). (1/5) Niranjan Kumar, PhD academic.oup.com/nar/article/do…

Measuring Hydroxyl Exchange Rates in Glycans Using a Synergistic Combination of Saturation Transfer and Relaxation Dispersion NMR | Journal of the American Chemical Society Molecular Biophysics Unit, IISc #HydroxylExchange #Glycans #NMR Magnetic Resonance News pubs.acs.org/doi/10.1021/ja…

Published version of the preprint now available! The link to the preprint thread is below. Congratulations Sanjna SANJNA!! Link: journals.physiology.org/doi/abs/10.115…

Out in Eur. Phys. J. Spec. Top., rdcu.be/dYTsy. We use our replica exchange with hybrid tempering (REHT) method to extract the Boltzmaan's weighted membrane-bound conformations of peripheral proteins. All work by grad student Chandramouli, a Physican turned Biophysicist.

Check out the special issue of "Proteins: Structure, Function, and Bioinformatics Vol 93 (1): Jan 2025" commemorating GN Ramachandran Centenary Molecular Biophysics Unit, IISc. Link: onlinelibrary.wiley.com/toc/10970134/2…

Flexibility of flanking DNA is a key determinant of transcription factor affinity for the core motif by Debostuti Ghoshdastidar and Manju Bansal at Molecular Biophysics Unit, IISc hubs.li/Q02YHVL70 Biophysical Journal highlight — An official journal of Biophysical Society

The last date for submitting online applications for Research programmes for the Academic Year 2025-26 has been extended till *06 April 2025* iisc.ac.in/admissions/

We are organizing a 2-day "AI in Biophysics" symposium from 28-29 April. We bring together leading experts to facilitate interdisciplinary and lively discussions. Website: sites.google.com/view/ai-in-bio… Poster abstract deadline: April 18 Registration deadline: April 24

The abstract submission is extended till 24th April. Register and attend the exciting symposium!