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How did the dramatic consolidation of academic publishing by for-profit publishers take place? Does a single paywalled article really cost $30 to $40? If you are ready to have your eyes opened to the seedy underbelly of academic publishing. Read ⬇️ theguardian.com/commentisfree/…

Like a Surgeon Cuttin’ for the very first time bitsandbasepairs.mattkrantz.com/p/bits-base-pa…

Are you looking for an article on what exactly goes into an academic tenure-track offer letter for physician-scientists? Yes. No. Maybe? Regardless, I give you “Academic Tenure-Track Offer Letters” from the Burroughs Wellcome Fund. Read ⬇️ bwfund.org/career-tool/ac…

Prioritizing candidate drugs with the highest likelihood of surviving the pipeline gauntlet—preclinical to approval—is critical. In their 2015 Nature Genetics article, Nelson et al investigated the role that genetic evidence for mechanism plays. Read ⬇️ nature.com/articles/ng.33…

Looking for a helpful mantra as a young physician-scientist? Might I suggest, "Shine on." Giovanni Davogustto outlines potential obstacles that one will encounter--and overcome--during graduate medical education. Read ⬇️ ahajournals.org/doi/10.1161/ci…

Chipotle Is my life bitsandbasepairs.mattkrantz.com/p/bits-base-pa…

What unites us is greater than what divides us Tyler Denk 🐝 beehiiv 🐝 Chipotle bitsandbasepairs.mattkrantz.com/p/bits-base-pa…

Have you ever been confused about the terminology of “cores” vs “threads” when it comes to talking about the central processing unit? If you, like me, have been in search of an article that can—without too much technical detail—explain the two, read ⬇️ blogs.vmware.com/professional-s…

For when the going gets tough, Dr. Anthony Fauci has a mantra. It’s a pseudo-Latin phrase that he learned while attending the Jesuit-run Regis High School, which translates to “Don’t let the bastards grind you down.” axios.com/2020/04/11/fau…

A virtual machine is—a computer inside a computer. Like a dream inside a dream—remember (not getting) Inception? To learn more about cloud-based virtual machines, I recommend checking out this article from Google Cloud cloud.google.com/learn/what-is-…

A favorite programming language for bioinformatics—R—was inspired by a similarly single letter named language, “S.” Co-created in 1993 by two statistics professors, Ross Ihaka and Robert Gentleman, “R” is so named also to pay homage to their first names. bitsandbasepairs.mattkrantz.com/p/bits-base-pa…

Dr. Carter You think he can save them? bitsandbasepairs.mattkrantz.com/p/bits-base-pa…

Feeling spicy? 🌶️ I wrote about Gordon Ramsay's wild ride on "Hot Ones," the science of heat, and some unexpected Pepto Bismol side effects 🖤👅 bitsandbasepairs.mattkrantz.com/p/hot-ones

Prank War Shoot your half-court shot Imagine this. You’re blind folded, at half-court, during halftime at a University of Maryland basketball game, setting yourself up for a shot potentially worth $500,00 in front of thousands of screaming fans... bitsandbasepairs.mattkrantz.com/p/prank-war

Golf in Space For what is considered a pastime, I don’t think golf could be anymore torturing. Imagine any other sport when you played just a couple of times a year causally with your good friends—and while enjoying their company—that could lead to... bitsandbasepairs.mattkrantz.com/p/golf-in-space

Low-pass Whole Genome Sequencing If you are a venture capitalist, I’d imagine seeing “1X” would make you sick to your stomach. However, if you are a bioinformatician, you are not in the business of “10X” returns on investment... bitsandbasepairs.mattkrantz.com/p/prank-war

Reproducibility Just because you did your analysis once doesn’t mean you can reproduce your result…tomorrow, the next day…or weeks, months or years from now. This is a very real concern as new data flows in... bitsandbasepairs.mattkrantz.com/p/golf-in-space

Judge Judy I was on an episode in 2003... bitsandbasepairs.mattkrantz.com/p/judge-judy

Small Talk What to say after "Hi"... bitsandbasepairs.mattkrantz.com/p/small-talk