Poster #ASCO24 #269 by our Dana-Farber Lank Center for Genitourinary Oncology super star Eddy Saad investigates SNP on IL7 associated with irAEs for Nivo (HR: 2.91, P=1.9e-03) v. Evo in CM025 trial (SNPxTRT P=0.003). Also #MeritAward recipient. DM if you have curated irAE data to replicate ! ASCO OncoAlert

With more photos coming ! Also Gil Morgan, MD Gil Morgan volunteered to be a goalie !

✨This #ASCO24 is happenning with incredibly great events! After working with the amazing OncoAlert #OncoAlertAF for a while, it is a really great privilege to be announced as an OncoAlert faculty😍 Huge thanks to my colleagues in #OncoAlertAF team and OncoAlert faculty and

Thank you GU Oncology Now for featuring our multi-center study on outcomes of subsequent therapy following RCC recurrence after adjuvant immunotherapy. guoncologynow.com/post/sequentia… Talal El Zarif, MD Toni Choueiri, MD Dana-Farber Lank Center for Genitourinary Oncology

1. 🚨Excited to share our latest article, co-led with Talal El Zarif, MD, now published in Cell Reports! doi.org/10.1016/j.celr… Immense gratitude to my amazing mentors Sylvan Baca MD PhD (Hiring!) Toni Choueiri, MD #MatthewFreedman for their crucial support. #BacaLab Dana-Farber Lank Center for Genitourinary Oncology Yale Medicine

🚨Out now Clinical Cancer Research! We demonstrate accurate non-invasive detection of small cell transformation in EGFRm lung adenocarcinoma through epigenomic cfDNA profiling! Led by @Cbmeador Xintao & guided by Jacob Berchuck #MattFreedman Dana-Farber Mass General Cancer Center doi.org/10.1158/1078-0…

⁉️What is the relation between clonal hematopoesis and RCC🤔🧐 Valisha from Dana-Farber Lank Center for Genitourinary Oncology is discussing the topic in a great presentation at #KCRS24 ⭐️🌟⭐️ Toni Choueiri, MD Maxine Sun David Braun Sasha Gusev

Stellar talk by 🌟 Clara Steiner presenting a pilot study of an implantable microdevice evaluating drug response in RCC in vivo! Wenxin (Vincent) Xu Toni Choueiri, MD #JonasLab #KCRS24 KidneyCAN OncLive.com Dana-Farber Lank Center for Genitourinary Oncology

The #INTerpath-004 trial explores the combination of pembro + personalized mRNA #vaccine for the adjuvant treatment of pts with RCC. Inspiring talk by Toni Choueiri, MD at #KCRS24! KidneyCAN Dana-Farber Lank Center for Genitourinary Oncology OncLive.com

Thanks to Marc Machaalani, of Dana-Farber, for sitting down with us at #KCRS24 to talk about the inhibition of AXL and c-Met in RCC! Check out our site for more meeting highlights! #kcsm onclive.com/conference/kid…

🚨Oral abstract session: brilliant postdoc fellows Karl Semaan, MD, MSc and Eddy Saad casually sitting and presenting next to giants in the field!⭐️ IM residency program, take notes: they are applying this cycle! #KCRS24 OncoAlert KidneyCAN

Our ⁦Dana-Farber Lank Center for Genitourinary Oncology⁩ ⁦Karl Semaan, MD, MSc⁩ and ⁦Eddy Saad⁩ presenting #KCRS24 ably mentored by ⁦Sylvan Baca MD PhD (Hiring!)⁩ and ⁦Sasha Gusev⁩ ⁦Dana-Farber⁩ ⁦Harvard Medical School⁩

Superstar Eddy Saad elegantly discussed his work validating the association of an IL7 SNP with irAEs from two phase III trials at #KCRS24! 🌟 Toni Choueiri, MD Sasha Gusev Eli Van Allen Dana-Farber Lank Center for Genitourinary Oncology OncoAlert KidneyCAN

🔝 Renee Maria Saliby rocks the stage discussing intermediate endpoints for efficacy of ICI-based regimens from IMDC RWD! #KCRS24 Toni Choueiri, MD Daniel Heng David Braun Dana-Farber Lank Center for Genitourinary Oncology Yale Internal Medicine OncoAlert

Wrapped up #KCRS24 #AcceleratingCures 🏈⚽️! It was such a privilege to meet and learn from so many brilliant minds. Looking forward to #KCRS25 and continuing to advance renal cell carcinoma research! 🔬

1/ 🚨 Just in European Urology , our study on first-line systemic therapy following adjuvant immunotherapy in renal cell carcinoma. Effort co-led with Talal El Zarif, MD, with amazing mentorship from Daniel Heng Toni Choueiri, MD sciencedirect.com/science/articl… Dana-Farber Lank Center for Genitourinary Oncology Yale School of Medicine OncoAlert

Our study on sex differences in Xp11 translocation renal cell carcinoma is out Cell! We ascribe a genetic basis to the female bias in tRCC, which is driven by a translocation of the TFE3 gene on the X chromosome. w Zhang lab @danafarbernews bit.ly/4dtpNtP 🧵1/

1/ Results from #LITESPARK-005 are out NEJM! The phase 3 trial that led to HIF-2 inhibitor Belzutifan (BEL) U.S. FDA approval Dec 2023 in pretreated pts w/ #ccRCC. Presentation #ESMO24 @myEsmo Check it out: nejm.org/doi/full/10.10…

Liquid biopsy in renal cell carcinoma | The Oncologist | with Marc Machaalani Karl Semaan, MD, MSc Marc Eid Rashad Nawfal, MD Razane El Hajj Chehade Sylvan Baca MD PhD (Hiring!) from Dana-Farber Lank Center for Genitourinary Oncology academic.oup.com/oncolo/advance…

🩸🧬Liquid biopsy is transforming cancer detection and monitoring, offering noninvasive insights. Recent studies show that ctDNA levels correlate with outcomes in RCC. Could emerging technologies enhance this? Marc Machaalani Karl Semaan, MD, MSc Marc Eid Rashad Nawfal, MD Razane El Hajj Chehade