We are delighted to share our latest publication! It’s a useful resource to the organoid community, but also uncovers some interesting biology about how tissue shape influences cell fate. Check out the thread below from first author Ilaria Chiaradia! dlvr.it/Sx38s6

Interested in postdoctoral training in fundamental neurobiology in an environment of a world-leading R&D unit, apply to have the best of both worlds! Please RT 1/5

Wonderful time and science yesterday at Waisman Center. Thanks for the opportunity to share our work!

This week in Science, Science Advances, and Science Translational Medicine, the #PsychENCODE Consortium lay out findings based on examining human brains at the single-cell level. Learn more: scim.ag/73Y #DecodingTheBrain

Our paper on splicing isoforms in developing human brain is finally out in Science Magazine! So grateful to Luis de la Torre-Ubieta and Michael Gandal for letting me be part of this amazing work. Congrats Ashok Patowary, PhD Pan Zhang Connor Jops! science.org/doi/10.1126/sc…

Very proud of this incredible team which led this innovative work to move us closer to understanding the impact of isoform diversity in the developing brain and neuropsychiatric disorders.

How do quantities of brain cells – the fundamental unit of life – differ in Alzheimer’s disease, schizophrenia and autism? Our work on cell-type proportion shifts using methylomics is just out in Science Advances #PsychENCODE Michael Gandal Daniel Vo science.org/doi/10.1126/sc… 🧵

New in Science Magazine: Our paper mapping gene/isoform/splicing regulation at pop-scale during human #neurodevelopment. Major developmental shifts in #genetic reg., New colocalized risk genes at ~60% of #psych #GWAS loci. #PsychENCODE24 science.org/doi/10.1126/sc…

New from Geschwind Lab @ UCLA: As part of the PsychENCODE Consortium, we performed single nucleus RNA and ATAC sequencing on ASD and Control brain samples to identify cell type–specific changes and the cellular regulatory networks perturbed by genetic risk factors. (1/)

Come see our work studying mechs of cortical development and neurodevelopmental disorders at #SfN24. Pstr. 257.12 / A12, Oct 8, 11-12p Pstr. 317.24 / A22, Oct 8, 4-5p We have openings for scientists with expertise in genomics interested in neuroscience. Come meet me at SFN!

Interested in the role of gene-isoforms in cortical development? Come see our work at #SfN24 today. Poster A12 8-12p.

📢 Our center is recruiting MULTIPLE new faculty working in stem cell research and regenerative medicine! Apply today to join UCLA's highly collaborative multi-disciplinary research environment: recruit.apo.ucla.edu/JPF09745

Re-upping this ad for a #postdocposition in our lab 🧠 🧬🔬 RT appreciated 🙏

1/ I am beyond thrilled to share our new paper in Cell! We explored the regulatory principles underlying pleiotropy in psychiatric disorders. cell.com/cell/abstract/…

Here is a press release by ⁦UCLA Health⁩ that nicely summarizes the key findings from our paper published today ⁦Cell⁩. uclahealth.org/news/release/m…

I’m honored to join Fred Hutch as Professor and Program Head of Biostatistics, and as the Donald and Janet K. Guthrie Endowed Chair in Statistics. Excited to be part of a deeply collaborative and scientifically vibrant community with a rich legacy of impact.