pbs.org/wgbh/nova/arti… See what Dr. Ilhem Messaoudi Messaoudi Lab has to say.

Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome science.sciencemag.org/content/early/…

Happy to share our recent insights into eukaryotic mRNA 3' end processing where we dissect the molecular interactions of hFip1. It took only a pre-print to make me tweet :) Thanks to everyone involved! @MartinJinek biorxiv.org/content/10.110…

New preprint from our lab and a great collaboration with Georg Seelig ! The anti-cancer compound JTE-607 reveals hidden sequence specificity of the mRNA 3' processing machinery biorxiv.org/content/10.110…

Excited to share our new work on direct protein-based genome editing in primary cells. We termed it Peptide-Assisted Genome Editing (PAGE) CRISPR-Cas platform. This platform allows rapid and effective editing of primary cells with minimal toxicity. go.nature.com/3LB007T

So incredibly proud of my wonderful undergrad, Alice, who did an amazing job presenting her research at the UCI UROP Symposium today!! (Redacted to create anticipation for upcoming findings 🤫)

It was a wonderful 6 years spent in Yongsheng Shi Lab and I’m so happy we all graduated together Kristianna and Lindsey Soles 🌻 !!!

Finished "Bacteriophage T4 Infection" this morning. The thin white line at left, which folds up and down 10 times, depicts the length of the T4 genome. After I add a few finishing touches and make sure I haven't forgotten anything, I'll put the full-size file rcsb pdb 💉🧬💻🔬💊🌱🧠🦠.

Close up of the newly-infected bacterial cell from "Bacteriophage T4 Infection." I drew the illustration in Photoshop at a scale of 1 pixel/nanometer.

The Many Shapes of Bacteria #infographic #bacteria #microbes #biology #science #design #illustration #art #sciart #shapes #geometry #microbiology

Fantastic #cshlmRNA 2023 conference with Lindsey Soles 🌻 and Yongsheng Shi!!! 2nd cold spring harbor conference that I attended but 1st one in person and 1st one attending as a postdoc 🎓 Wait for me to come back in 2025!

Congrats Roberto and Emily!! Heard this story a few times in the past and nice to see it finally came out!

BREAKING NEWS The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.

I'm glad that our paper on the anticancer compound JTE-607 has come out in 2023 in NatureStructMolBiol ! Congrats to first authors Liang Liu and Angela Yu rdcu.be/dtqBa

Excited to share my most recent work in NatureStructMolBiol on mRNA 3' processing and the anticancer compound JTE-607: rdcu.be/dtqBa. A huge thank you to my PI Yongsheng Shi, my collaborators Angela Yu and Georg Seelig, and amazing lab mates Yoseop Yoon Lindsey Soles 🌻 and Marielle Valdez

Interested in working on RNA processing and degradation? Come join us! My lab is recruiting at all levels!

My department is hiring a tenure-track faculty focusing on RNA biology! UC Irvine has a large, vibrant and super supportive RNA community! Come join us! recruit.ap.uci.edu/JPF09320

In this Review, La Fleur et al. dive into the world of massively parallel reporter assays (MPRAs) in studying RNA and gene regulation. Yongsheng Shi Georg Seelig Learn more about the power of MPRAs in therapeutic design when coupled with machine learning: ➡️ tinyurl.com/gd351800

Start the new year with a new publication! Led by the talented postdoc Yoseop Yoon ! RBBP6 anchors pre-mRNA 3′ end processing to nuclear speckles for efficient gene expression: Molecular Cell cell.com/molecular-cell…