An important #FathersDay message from me…WEAR A HELMET ! This week I had a bad accident while riding my bike in CT. I'm doing ok and I’m thankful for all the doctors, nurses and staff at @LMHospital who looked after me but most thankful for my helmet that saved my life. Be Safe

Congratulations Edith! Excellent news for The Crick

Many congratulations to all the new EMBO members! So many fantastic scientists in this list! Steve West Lab Costa Lab Sebastian Glatt Juha Huiskonen Martin Jinek Niakan Lab SpillantiniLab the Peijun Zhang Lab AdelmanLab among many others!

New #LMBResearch from Pablo Alcón & Lori Passmore has identified the molecular mechanism by which the FANCD2-FANCI protein complex identifies sites of DNA damage. Read more: www2.mrc-lmb.cam.ac.uk/combining-sing… With Artur Kaczmarczyk Korak Ray David Rueda Puck Knipscheer (Hubrecht Institute) & Julian Sale

Very cool structure-function story by Pablo Alcón (Passmore lab) and co. D2I complex filmed in action sliding on gapped DNA and interacting with ds-ssDNA junctions. Similar behavior to what we've seen with full-length human BRCA2. Congrats all 👏 Korak Ray Artur Kaczmarczyk David Rueda

Check out the latest work from Lori Passmore and David Rueda, out now! It was a great pleasure working with Pablo Alcón and Artur Kaczmarczyk on this amazing story!

So happy to see this story out! Dynamic single-molecule and cryo-EM data reveal how the FANCD2-FANCI complex detects damaged DNA sites. Huge thanks to Pablo Alcón, Lori Passmore, and Korak Ray for this wonderful collaboration during my postdoc at David Rueda MRC Laboratory of Medical Sciences (MRC LMS)

We are excited that Puck Knipscheer and Themis Liolios contributed to this research from the MRC Laboratory of Molecular Biology in Cambridge on DNA repair, which was published in Nature today! Read more here: hubrecht.eu/dna-repair-mys…

Fantastic work from Pablo Alcón from the Passmore Group Lori Passmore in colaboration with David Rueda, Artur Poldan, Korak Ray and Julian Sale and Puck Knipscheer. Please read, it's a beautiful study showing how DNA damage is recognized.

FANCI that! New #LMSResearch from David Rueda has solved the decades long mystery of how DNA damage by sunlight, alcohol and pollution is identified so it can be repaired. This discovery opens up opportunities for improved cancer treatments. lms.mrc.ac.uk/fanci-that-dec…

Check out NuA4/TIP60 in Science Magazine . We show how this molecular Swiss army knife integrates histone exchange and acetylation in one complex to maintain genome stability 🧬 Congrats to zhenlin and @mameri_amel who co-first authored this work! 🧵⬇️ twtr.to/157Oh

We are excited to share new mechanistic insights into DNA replication fidelity! How does human DNA Polymerase Epsilon recognise and proofread errors made during synthesis? 🧬 Read NatureStructMolBiol nature.com/articles/s4159…

Looking forward to this!!

My favourite discovery ever has just come online. Can I please tell you about some seriously wacky molecular biology? The story starts with a reverse transcriptase that SOMEHOW defends bacteria from viruses. (👇 I recommend sound ON for the video 🎹) 1/

Very excited for my first day as a Lecturer in Genome Stability/PI GDSC to start a new lab focussing on DNA damage checkpoint control using structural biology. A career dream come true!

Looking forward to this!