Our new work about temperature sensitivity of #TRPA1 is out now mdpi.com/603450 MDPI #pain #inflammation #sensory #Physiolrev #openaccess #MDPI #heat #nociception

Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel. - PubMed - NCBI ncbi.nlm.nih.gov/pubmed/31866091

Volatile anaesthetics inhibit the thermosensitive nociceptor ion channel transient receptor potential melastatin 3 (TRPM3). #ionchannels Biochem Pharmacol zpr.io/tyLPy

Involvement of TRPC4 and 5 Channels in Persistent Firing in Hippocampal CA1 Pyramidal Cells. #ionchannels Cells zpr.io/tuV6y

We have been enchanted by the TRPA1 channel for over 10 years. Happy to announce the publication of the perspective article gathering recent intriguing findings. frontiersin.org/article/10.338…

Congrats to Lund on new clues in understanding the calcium modulation of our beloved TRPA1 receptor: Calcium activates purified human TRPA1 with and without its N-terminal... sciencedirect.com/science/articl…

A Special Issue on #TRPA1 Channel is open for submission: mdpi.com/si/53959 #mdpiijms via IJMS MDPI

A Nature paper reports a single-step method to convert non-neuronal brain cells into functional neurons, demonstrated in isolated human cells and in mice. The technique is shown to reverse symptoms of Parkinson’s disease in a mouse model of the disease. go.nature.com/2VKke4L

Presenting cryoEM structures of full-length Glycine receptor in lipid membrane, now out in Nature Communications We had exciting collaboration with Mark Sansom for MD simulation. nature.com/articles/s4146…

My lab is looking for new post doctoral fellows (fully funded) interested in focusing on the intersection of RNA biology and chromosomal regulation in the immune, neural or any other interesting biology of their choice. Thanks much for RT.

Piezo2. Again...

Excellent review on chemical biology tools for studying #ionchannels by @LabPless @laninja2744 UCPH Healthscience Read it now 👉 buff.ly/35s32EU

Phosphorylation switch off on #TRPA1? mdpi.com/871446 via MDPI Found by our student Tyna during her master’s degree. Check the story and do not forget that the special issue of IJMS about TRPA1 is still open for contributions! mdpi.com/journal/ijms/s…

A Special Issue on #TRPA1 Channel is open for submission: mdpi.com/si/53959 #mdpiijms via IJMS MDPI

In our lab, two years ago... A: There's a drug that relieves cold-induced pain, but it's not known why... B: Let's see if it modulates TRPC5 - it should be cold-sensitive... The article's out, see for yourself. sciencedirect.com/science/articl…

The hours spent on single channel analysis paid off. Our paper characterizing the #ColdSensitivity of #TRPC5 #ionchannels has just been published. doi.org/10.1002/jcp.30…

🚨 Job alert 🚨 We have a open position for a PhD candidate at the Soehnlein Lab !🔬DM me for more project info and apply at jobs-sf.ukmuenster.de/job/UKM-Wissen… we are look forward to get to know and work with you. Please retweet 😃 Uniklinik Münster awaits you! (GUV to bring attention 😁)

Fellow adventurers on a quest to tame pain please note: Our article on TRPC5 and duloxetine has just been featured on Medicine Innovates. medicineinnovates.com/molecular-targ…

It was an absolute pleasure to measure the TRPV2! After years with TRPA1, which has its moods, recent experiences with TRPC5, which lives its own life regardless of the investigator's efforts, measuring a well-behaved TRPV2 was a refreshing experience. rdcu.be/c05YD

Khan et al. study the mechanisms by which TRPA1 channels contribute to mechanical and cold hypersensitivity, and show that the scaffold protein IQGAP1 is an essential part of this process. bit.ly/3PtaOFj