iFlpMosaics are now published Nature Methods. A compendium of novel genetic tools and related methods for inducing and analysing genetic mosaics in a high-throughput manner. nature.com/articles/s4159… Tweetorial 👇

Intermittent fasting triggers interorgan communication to suppress hair follicle regeneration: Cell cell.com/cell/fulltext/…

I am delighted to share our new study published in ⁦Nature Communications⁩ in which we uncover a common mechanism by which collagen signaling and matrix stiffness regulate stem cell multipotency in glandular epithelia. nature.com/articles/s4146…

Woohoo! Our latest preprint, from Madhura Nijsure Nijsure, is out today bioRxiv! YAP regulates periosteal expansion in fracture repair. biorxiv.org/content/10.110…

Excited to share this collaborative work with @Hadhjantonakis and dana_peer led by Vidur Garg reporting drastically different interconversion efficiencies between ESC and XEN, unique trajectories mimicking in vivo states, and key plasticity barriers. cell.com/developmental-…

Happy to publish our collaboration with Diane Mathis on the conservation of thymic mimetic cells in zebrafish, mice and humans. authors.elsevier.com/c/1kL0e3qNrUxu…

Excited to share a major breakthrough from the lab! D&D-seq is a new technology that bridges a key gap in single-cell multi-omics/genomics : the ability to map DNA:Protein (e.g., TFs or chromatin remodellers). Led by Ivan Raimondi, Wei-Yu Chi and Sang-Ho Yoon

🚨Why can’t mammals regenerate legs or arms like frog tadpoles or salamanders? Our preprint tackles (part of) this BIG question with surprising findings about oxygen sensing 🔗biorxiv.org/content/10.110… Happy New Year, everyone! 🎉 🐭 vs 🐸 #evodevo #regenerative #cellbio 🧵👇

We are thrilled to share our new single-cell foundation model, Tabula (preprint: biorxiv.org/content/10.110…; package: github.com/aristoteleo/ta…)—a privacy-preserving predictive foundation model for single-cell transcriptomics, leveraging federated learning and tabular modeling. Over

Well done! 🎉

The outer ear is a mammalian innovation but where did it come from? In our study in nature, Mathi Thiruppathy and colleagues find that the outer ear arose from modification of an ancestral gill program first originating in marine invertebrates. nature.com/articles/s4158… 1/n

New study from us: elifesciences.org/articles/98661 showing new functions for the fibroblast growth factor homologous factor (FHF) FGF13 in neurons. The roles for FHFs continue to expand! Author Susan Lin co-mentored by The Rajadhyaksha Lab

🚨 We’re hiring a Postdoctoral Fellow to study heart development/regeneration using zebrafish 🐟 & human cardioids ❤️! If you're passionate about stem cell biology, tissue regeneration, heart disease/repair, email me! 🔗 More info: caolab.net

report on myocardial patch in a human out in nature rdcu.be/d72c2

🚨We are hiring!🚨 We have postdoctoral positions available! If you're passionate about studying cardiac regeneration and development, join our team in vibrant and beautiful Montreal! Please help spread the word 🫶 For more details see here research.chusj.org/RECHERCHE/fi...

Excited to share our latest article. 7 years ago my then 9 year old son was diagnosed with K210del DCM. With the help of my colleagues Joseph C Wu, MD, PhD, Sakthivel Sadayappan, PhD, MBA and Enzo Porrello we identified an FDA approved drug that corrects the mutation. JCI - An FDA-approved drug

Super excited to share that our manuscript is finally OUT @CellSystems!!🚨 Cold and hot fibrosis define clinically distinct cardiac pathologies. cell.com/cell-systems/f…🧵(1/)

Congratulations ⁦Isha Jain⁩ and team on this amazing work! HypoxyStat, a small-molecule form of hypoxia therapy that increases oxygen-hemoglobin affinity: Cell cell.com/cell/fulltext/…

Paper alert🐟! Thrilled to share that our latest study “BMP signaling promotes zebrafish heart regeneration via alleviation of replication stress” nature.com/articles/s4146… is now live in Nature Communications. We show how BMP alleviates this stress via a conserved mechanism in mammals🐭

New lab preprint! We did a giant genetic screen for factors that help cells to divide into more than 2 (as can occur in cancer). Our top hit is an unnamed fly gene that has a human counterpart which is targeted by an FDA-approved drug for epilepsy. biorxiv.org/content/10.110…